Protein Alignment CG15556 and ADGRF3

DIOPT Version :9

• Sequence 1: NP_001247379.1
• Gene: CG15556 / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001138640.1
• Gene: ADGRF3 / 165082
• HGNCID: 18989
• Length: 1079
• Species: Homo sapiens
• Alignment Length: 721
• Identity: 155/721 - (21%)
• Similarity: 252/721 - (34%)
• Gaps: 195/721 - (27%)

  Fly   107 NERGIPIRRRCQIRNGNRVWQSLDHVTCRSAPELS--SSINLLAV--KSPPDMISQ-LSNLLTQT 166
            ::||| :||.|   ..:.||..: |.:|..|..|:  :...||..  .||.:.:.| |:.|..|.
Human   456 SKRGI-VRRLC---GADGVWGPV-HSSCTDARLLALFTRTKLLQAGQGSPAEEVPQILAQLPGQA 515

  Fly   167 QEKLAAADVFSISEIFDSLVK-----KPERNAAVVGDLMKICQKVMSTDNETLRVSADAN---AT 223
            .|..:.:|:.::......:.|     :.:.:...:.:|:....||:..|..:|...|.|.   |.
Human   516 AEASSPSDLLTLLSTMKYVAKVVAEARIQLDRRALKNLLIATDKVLDMDTRSLWTLAQARKPWAG 580

  Fly   224 NALLSNFEDYLDELSPTILKLNTTIFANSTEFTFHPL-FDMGVIVLKTSELRVFFVDPEVRNVSG 287
            :.||...|.....|.|                ..||. |.:..::|: |:|
Human   581 STLLLAVETLACSLCP----------------QDHPFAFSLPNVLLQ-SQL-------------- 614

  Fly   288 IVNFSGGNMSHFEMLHLSDNEEDIRAMKNLESAVFIPEKLWTQLKRKGASYLVFKVYTR--DSLF 350
                       |.....:|..........|::.  ||......|.|.|....:..:..|  |.|.
Human   615 -----------FGPTFPADYSISFPTRPPLQAQ--IPRHSLAPLVRNGTEISITSLVLRKLDHLL 666

  Fly   351 VETEEEIKRRPTSNVISITIPGLNDT--KLPGKLPFFLRNAKANETQFEGG-------------- 399
            .....:               ||.|:  ..||.:  .:.:..|.:..|..|
Human   667 PSNYGQ---------------GLGDSLYATPGLV--LVISIMAGDRAFSQGEVIMDFGNTDGSPH 714

  Fly   400 CGYWNYETWLS-DGISTSGGGSLEASSHPVILCHADHLTQFTFLLGVSKMQAGLDTNEDDHSLDV 463
            |.:|::..:.. .|.|..|..:..||:.|...|...|||.|:.|:..       .|..::.:|.:
Human   715 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSP-------HTVPEEPALAL 772

  Fly   464 ITNVGLTLSLLGLLMIFITAAVFKSFRTLASTKILLNLCAALGLQLLFFLILSQSHLLEQLEQSE 528
            :|.|||..|:|.||:..  ...:..:|.:...||.....||| |.::|.|:.:.:..|.....|.
Human   773 LTQVGLGASILALLVCL--GVYWLVWRVVVRNKISYFRHAAL-LNMVFCLLAADTCFLGAPFLSP 834

  Fly   529 SER---CTLVGAVMQYLLLVVFSWMFIIGFLQYQRYVRVIGVNHPRHYILMSAVAAWTLPLIPTL 590
            ..|   |.....:..:|.|..|.||.                             |..|.|...|
Human   835 GPRSPLCLAAAFLCHFLYLATFFWML-----------------------------AQALVLAHQL 870

  Fly   591 LVVFLEPGSYR--PNNSSMDYPILCYPSGY-GLSLGVILPIG----------------LITVANA 636
            |.||.:...:|  |....:.|  || |.|. |::||:.||.|                |.|....
Human   871 LFVFHQLAKHRVLPLMVLLGY--LC-PLGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGP 932

  Fly   637 IL--VGYISWSVYTALF--------------KRDLIFKQLGLFVLLFFLLGITWIFGLCTYF-DF 684
            :|  :|.....:..|:.              ||..:...:...::|..:.|:||..||.|.. :.
Human   933 VLAIIGVNGLVLAMAMLKLLRPSLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEV 997

  Fly   685 GRIFAYLFCLTATLQGFVLFLYFIVFNKENQRAWLGLCCNSSKKRNQQTIQMPTDSI------LQ 743
            ..:..|:|.:..||||..:.|:..:.:::.|.|.....|.:         |.|:.:|      ||
Human   998 STVPHYIFTILNTLQGVFILLFGCLMDRKIQEALRKRFCRA---------QAPSSTISLVSCCLQ 1053

  Fly   744 GLSHSS 749
            .||.:|
Human  1054 ILSCAS 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	58/260 (22%)
ADGRF3	NP_001138640.1	HRM	431..477	CDD:280888	9/25 (36%)
		GPS	713..758	CDD:280071	13/44 (30%)
		7tm_4	770..1016	CDD:304433	67/280 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810