Protein Alignment CG15556 and adgre14

DIOPT Version :9

• Sequence 1: NP_001247379.1
• Gene: CG15556 / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_021330419.1
• Gene: adgre14 / 108182849
• ZFINID: ZDB-GENE-131120-49
• Length: 505
• Species: Danio rerio
• Alignment Length: 574
• Identity: 138/574 - (24%)
• Similarity: 218/574 - (37%)
• Gaps: 129/574 - (22%)

  Fly   217 SADANAT------NALLSNFEDYLDELSPTILKLNTTIFANSTEFTFHPLFDMGVIVLKTSELRV 275
            |:.||..      |.:|.|.|    ||..|::|...|  :.:..||           |...|.||
Zfish    13 SSSANPNELTSYGNRVLINNE----ELMSTLVKQTDT--SANVSFT-----------LADVEGRV 60

  Fly   276 FFVDPEV----------RNVS------GIVNFSGGNMSHFEMLHLSDNEEDIRAMKNLESAVFIP 324
            |.|.|.|          ||.|      ||.|.:.|..| ..::.|..|     .|:||..|.|
Zfish    61 FMVGPHVTLDEIPRLHTRNCSIDIDLIGIANNNNGTRS-AAVIFLGYN-----TMENLLKADF-- 117

  Fly   325 EKLWTQLKRKGASYLVFKVYTRDSLFVETEEEIKRRPTSNVISITIPGLNDTKLPGKLPFFLRNA 389
                                     |..|.:.:... .|:|||:|:|...:|.|...:.|..|:.
Zfish   118 -------------------------FNATNDTVNTM-MSSVISVTLPKTTNTALSKPVNFTFRHI 156

  Fly   390 KANETQFEGGCGYWNYETWLSDGISTSGGGSLEASSHPVILCHADHLTQFTFLLGVSKMQAGLDT 454
            :..:......|.|||...|:.||.|...      ::....:|...||:.|..:     ||.....
Zfish   157 REFDPSGSFSCVYWNISKWIVDGCSVLN------TNRSFTVCSCVHLSTFALI-----MQTRSHP 210

  Fly   455 NEDDHSLDVITNVGLTLSLLGLLMIFITAAVFKSFRTLASTKI----LLNLCAALGLQLLFFLIL 515
            .|.|..|:|:..|.:.:.||     |.:.|:....|...|..:    .:|:|.:|.|..|.|| |
Zfish   211 PESDSLLNVLNVVCVIVGLL-----FFSLALLTFTRCQWSPGVNNVARINICISLLLAHLLFL-L 269

  Fly   516 SQSHLLEQLEQSESERCTLVGAVMQYLLLVVFSWMFIIGFLQYQRYVRVIGVNHPRHYIL---MS 577
            :|..|  .|.:.:...|.|:..::.:|.|..|.||||...|.:.....:..::.....:|   :.
Zfish   270 TQQFL--SLIRRQKVLCMLISGLLHFLFLSGFVWMFIEAVLLFICVKNLSQISSQMKNVLRNKLL 332

  Fly   578 AVAAWTLPLIPTLLVVFLEPGSYRPNNSSMDYPILCYPSGY-GLSLGVILPIGLITVANAILVGY 641
            .|..:.:.|:...:...:.|..|....        |:...: |.....:.|:.:|...|.||...
Zfish   333 CVIGYAVALVVVSISAAVVPNGYGSEK--------CWIQMHKGFIWSFLGPVTIIIALNVILFIS 389

  Fly   642 ISWSVYTALFK-----------RDLIFKQLGLFVLLFFLLGITWIFGLCTYFDFGRIFAYLFCLT 695
            |.:|:.:|..|           :.::||.|..||    :||.:||.|..|  :..::...||.:.
Zfish   390 IGFSLKSAFKKLNADVSQLNQTKIVMFKTLAQFV----VLGCSWILGFFT--NSSKVLEILFLIL 448

  Fly   696 ATLQGFVLFLYFIVFNK----ENQRAWLGLCCNSSKKRNQQTIQMPTDSILQGL 745
            .:.||..:||.:.|.||    |.::.:..|......|....:.:...||.:.||
Zfish   449 NSQQGTFIFLIYCVLNKGIRQEYRKLFTSLYSGLKPKNFNWSSENTEDSTIHGL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	55/240 (23%)
adgre14	XP_021330419.1	GPS	167..205	CDD:197639	12/48 (25%)
		7tm_GPCRs	214..476	CDD:333717	68/283 (24%)
		TM helix 1	217..241	CDD:320095	7/28 (25%)
		TM helix 2	250..271	CDD:320095	8/21 (38%)
		TM helix 3	285..307	CDD:320095	8/21 (38%)
		TM helix 4	331..347	CDD:320095	2/15 (13%)
		TM helix 5	365..388	CDD:320095	6/22 (27%)
		TM helix 6	412..435	CDD:320095	10/26 (38%)
		TM helix 7	439..464	CDD:320095	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810