Protein Alignment Ktch and adgre9

DIOPT Version :10

• Sequence 1: NP_651845.2
• Gene: Ktch / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_073762995.1
• Gene: adgre9 / 101883848
• ZFINID: ZDB-GENE-121214-61
• Length: 674
• Species: Danio rerio
• Alignment Length: 707
• Identity: 150/707 - (21%)
• Similarity: 251/707 - (35%)
• Gaps: 186/707 - (26%)

  Fly    90 VEKTRVGQKANLRDLCLNER--GIPIR---RRCQIRNGNRVWQSL-----DHVTCRSAPELSSSI 144
            ||:..:||.........|.:  |...:   ..|.|.....::..|     |..:|....::::|:
Zfish    89 VERACLGQNTACMAYSCNSKSSGCSCKLGSYNCSINCNYDIYSDLCDCRADTHSCTCLGDMTTSV 153

  Fly   145 NLLAVKSPPDMI---SQLSNLLTQTQEKLAAADVFSISEIFDSLVKKPERNAAVVGDLMKICQKV 206
            .     ||...:   :.|.||::....:|:..|..:...:.|:                  .|..
Zfish   154 G-----SPNQTVASTTNLLNLISNMSGQLSPTDAGNFLSVVDA------------------AQMK 195

  Fly   207 MSTDNETLRVSADANATNALLSNFEDYLDELSPTILKLNTT---IFANSTEFTFHPL------FD 262
            :||.:..:..|...:..||.|:.||:.:..|  .:...|.|   |..|:||.|...:      .|
Zfish   196 VSTSDSPVEKSTLVSFGNAYLNAFENLVSAL--VVATDNMTVKNIALNNTEVTVLAIGVNASAAD 258

  Fly   263 MGVIVLKTSELRVFFVDPEVRNVSGIVNFSGGNMSHFEMLHLSDNEEDIRAMKNLESAVFIPEKL 327
            :..|..||::|.:..:....:::|
Zfish   259 IPPIYTKTAQLEIDLIGIAKQSIS----------------------------------------- 282

  Fly   328 WTQLKRKGASYLVFKVYTRDSL----FVETEEEIKRRPTSNVISITIPGLNDTKLPGKLPFFLRN 388
                  |.||.........||:    |..|.|...:...|.|||.|:...|:|.|...:.|.|::
Zfish   283 ------KSASVAFVSYSAMDSILKPDFFNTSENTVKTMMSTVISATLSQTNNTALTKPVNFTLKH 341

  Fly   389 AKANETQFEGGCGYWNYETWLSDGISTSGGGSLEASSHPVILCHADHLTQFTFLLGVSKMQAGLD 453
            .:....:....|.|||...|:.||.|.....    |||.|  |...||:.|..::..|
Zfish   342 IQGFNPKSSLSCVYWNDSEWIVDGCSVLNSN----SSHTV--CSCVHLSTFALIMQTS------- 393

  Fly   454 TNEDDHSLDVITNVGLTLSLLGLLMIFITAAVFKSFRTL-----ASTKILLNLC-AALGLQLLFF 512
             :....|.|::..:.|...::||  :|.:.|:. ||...     .:....:|:| :.|...|||
Zfish   394 -STPPESSDLLELLNLVCVIVGL--VFFSLALL-SFALCQWSPGVNNVARINICISLLSAHLLF- 453

  Fly   513 LILSQSHLLEQLEQSESERCTLVGAVMQYLLLVVFSWMFIIGFLQYQRYVRVIGVNHPRHYILMS 577
             :|:|..|  .|.:.:...|..:..::.:|.|..|.||||...|.:.....:..::..:..:|.|
Zfish   454 -LLTQQFL--SLIRPQQVFCVAIAGLLHFLFLSAFVWMFIEAVLLFICVQNLSRISSKKKEVLSS 515

  Fly   578 ---AVAAWTLPLIPTLLVVFLEPGSYRPNNSSMDYPILCYPSGYG-------------------- 619
               .|..:.|.|:    ||.:..|              ..|.|||
Zfish   516 GFLCVIGYVLALV----VVGVSIG--------------LVPEGYGSEQCWIKTAEGFIWSFLGPV 562

  Fly   620 ---LSLGVILPIGLITVANAILVGY---ISWSVYTALFKRDLIFKQLGLFVLLFFLLGITWIFGL 678
               |:|..|..|.::...|:.|...   :|....|.:    |.||.|..||    :||..||.|.
Zfish   563 CVILALNTIFFIKIVLTLNSTLKNLNAEVSQMKQTKI----LAFKTLSQFV----VLGCPWILGF 619

  Fly   679 CTYFDFGRIFAYLFCLTATLQGFVLFLYFIVFNKENQRAWLG----LCCNSSKKRNQ 731
              :.:...:...||.:..:.||..:|:.:.|.|.|.::.:..    ||...|.|.|:
Zfish   620 --FINGSEVLEILFLVLNSQQGTFIFVIYCVLNNEIRQQYKNCFTCLCSGHSIKCNK 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktch	NP_651845.2	7tmB2_Adhesion	458..718	CDD:320168	67/294 (23%)
		TM helix 1	460..485	CDD:320168	6/24 (25%)
		TM helix 2	495..517	CDD:320168	7/22 (32%)
		TM helix 3	533..559	CDD:320168	8/25 (32%)
		TM helix 4	574..594	CDD:320168	6/22 (27%)
		TM helix 5	617..646	CDD:320168	10/54 (19%)
		TM helix 6	656..682	CDD:320168	10/25 (40%)
		TM helix 7	686..711	CDD:320168	6/24 (25%)
adgre9	XP_073762995.1	None