DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3T and PRE1

DIOPT Version :9

Sequence 1:	NP_651843.1	Gene:	Prosalpha3T / 43679	FlyBaseID:	FBgn0261395	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_010928.1	Gene:	PRE1 / 856731	SGDID:	S000000814	Length:	198	Species:	Saccharomyces cerevisiae

Alignment Length:	153	Identity:	38/153 - (24%)
Similarity:	64/153 - (41%)	Gaps:	48/153 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 VGLLAKNGVLLATERSV-----------DKLMDTSIPVPRISWLNENIACCATGNTA------DG 82
            :|:..::.|:||:.::|           ||....| |...:|:..|      .|:|.      ..
Yeast     5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLS-PHTLMSFAGE------AGDTVQFAEYIQA 62

  Fly    83 NVLVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQ-YGGKRPFGVSFLYMGWDCRFGF-Q 145
            |:   ||..|.:.|     |:.|  |.|::.  ::|...: ...:||:.|:.|..|:|.:... :
Yeast    63 NI---QLYSIREDY-----ELSP--QAVSSF--VRQELAKSIRSRRPYQVNVLIGGYDKKKNKPE 115

  Fly   146 LYQSD--------PSG--NYSGW 158
            |||.|        |.|  .|||:
Yeast   116 LYQIDYLGTKVELPYGAHGYSGF 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	38/153 (25%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:294319	38/153 (25%)
PRE1	NP_010928.1	proteasome_beta_type_2	1..194	CDD:239727	38/153 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900