DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosalpha3T and PRE9

DIOPT Version :9

Sequence 1:	NP_651843.1	Gene:	Prosalpha3T / 43679	FlyBaseID:	FBgn0261395	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_011651.3	Gene:	PRE9 / 853036	SGDID:	S000003367	Length:	258	Species:	Saccharomyces cerevisiae

Alignment Length:	246	Identity:	107/246 - (43%)
Similarity:	155/246 - (63%)	Gaps:	13/246 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ARFFDSRTTIFSPEGRLYQVEYAMEAASQSGTCVGLLAKNGVLLATERSV-DKLMDTSIPVPRIS 65
            :|.:|||||||||||||||||||:|:.|.:||.:|::|.:|::||.||.| ..|::......::.
Yeast     3 SRRYDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLY 67

  Fly    66 WLNENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQYGGKRPFG 130
            .||:.||....|.|||..:|:|..|:.||.|...:.|.||.|.||..|.||||.|||:||.||||
Yeast    68 KLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFG 132

  Fly   131 VSFLYMGWDCRFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPSVEEAKDVA 195
            |||:|.|:|.|:|:|||.|:|||||:||||..:|..:.||..:||.:...    ...|::|.::|
Yeast   133 VSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKD----DMKVDDAIELA 193

  Fly   196 IKVMGMTLGRDSLTPEKLEIAFVQRYGNTTVFHILEKNEIHRLIERNNNLK 246
            :|.:..|....:||.::||.|.:::..|        ..|:::.|.:...:|
Yeast   194 LKTLSKTTDSSALTYDRLEFATIRKGAN--------DGEVYQKIFKPQEIK 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	106/239 (44%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:294319	103/215 (48%)
PRE9	NP_011651.3	proteasome_alpha_type_4	4..216	CDD:239721	103/215 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345965
Domainoid	1	1.000	193	1.000	Domainoid score	I617
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I665
Isobase	1	0.950	-	0	Normalized mean entropy	S260
OMA	1	1.010	-	-		QHG54118
OrthoFinder	1	1.000	-	-		FOG0003645
OrthoInspector	1	1.000	-	-		otm46517
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2516
TreeFam	1	0.960	-	-
	13	12.810