DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3T and PAC1

DIOPT Version :9

Sequence 1:	NP_651843.1	Gene:	Prosalpha3T / 43679	FlyBaseID:	FBgn0261395	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_188850.1	Gene:	PAC1 / 821774	AraportID:	AT3G22110	Length:	250	Species:	Arabidopsis thaliana

Alignment Length:	245	Identity:	117/245 - (47%)
Similarity:	166/245 - (67%)	Gaps:	8/245 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARFFDSRTTIFSPEGRLYQVEYAMEAASQSGTCVGLLAKNGVLLATERSV-DKLMDTSIPVPRI 64
            |:|.:||||||||||||||||||||||...:|:.:|:|:|:||:|..|:.| .||:.||....::
plant     1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEKM 65

  Fly    65 SWLNENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQYGGKRPF 129
            ..:::::||...|..:|.|:|:|..|:.||:|.|.:.|.:|.||||.:|||.||.|||:||.|||
plant    66 YKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQFGGLRPF 130

  Fly   130 GVSFLYMGWDCRFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPSV-EEAKD 193
            |||||:.|||...|||||.|||||||.||||..:|..:.||..:|:::     |...:. |||.:
plant   131 GVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQD-----YKDDATREEAVE 190

  Fly   194 VAIKVMGMTLGRDSLTPEKLEIAFVQRYGNTTV-FHILEKNEIHRLIERN 242
            :|:||:..|:...|||.||||:|.|....:.|| :|:.....:.:|:.::
plant   191 LALKVLTKTMDSTSLTSEKLELAEVYLTPSKTVKYHVHSPESLTKLLVKH 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	117/242 (48%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:294319	111/216 (51%)
PAC1	NP_188850.1	proteasome_alpha_type_4	3..215	CDD:239721	111/216 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	210	1.000	Domainoid score	I795
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I898
OMA	1	1.010	-	-		QHG54118
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003645
OrthoInspector	1	1.000	-	-		mtm1202
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2516
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.940