Protein Alignment Prosalpha3T and PSMA5

DIOPT Version :10

• Sequence 1: NP_651843.1
• Gene: Prosalpha3T / 43679
• FlyBaseID: FBgn0261395
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_002781.2
• Gene: PSMA5 / 5686
• HGNCID: 9534
• Length: 241
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 81/248 - (32%)
• Similarity: 127/248 - (51%)
• Gaps: 28/248 - (11%)

  Fly     5 FDSRTTIFSPEGRLYQVEYAMEAASQSGTCVGLLAKNGVLLATERSV-DKLMDTSIPVPRISWLN 68
            :|.....|||||||:|||||:||.....|.:|:....||.||.|:.: ..||:.| .:.:|..::
Human     8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPS-SIEKIVEID 71

  Fly    69 ENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCE---QLVTNLCDIKQAYTQYGGK---- 126
            .:|.|..:|..||...|:::.|:..|.:.|.:.|.:..|   |.|:||.      .|:|.:
Human    72 AHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA------LQFGEEDADP 130

  Fly   127 ----RPFGVSFLYMGWDCRFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPS 187
                |||||:.|:.|.|.: |.||:..||||.:....|..||..|..|...|| |::.|   |.:
Human   131 GAMSRPFGVALLFGGVDEK-GPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQ-EVYHK---SMT 190

  Fly   188 VEEAKDVAIKVMGMTLGRDSLTPEKLEIAFVQRYGNTTVFHILEKNEIHRLIE 240
            ::||...::.::...: .:.|....:|:|.||...|   ||:..|.|:..:|:
Human   191 LKEAIKSSLIILKQVM-EEKLNATNIELATVQPGQN---FHMFTKEELEEVIK 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:469781	73/224 (33%)
PSMA5	NP_002781.2	proteasome_alpha_type_5	8..220	CDD:239722	73/224 (33%)