Protein Alignment Prosalpha3T and PSMA4

DIOPT Version :9

• Sequence 1: NP_651843.1
• Gene: Prosalpha3T / 43679
• FlyBaseID: FBgn0261395
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_001096137.1
• Gene: PSMA4 / 5685
• HGNCID: 9533
• Length: 261
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 138/243 - (56%)
• Similarity: 182/243 - (74%)
• Gaps: 4/243 - (1%)

  Fly     1 MARFFDSRTTIFSPEGRLYQVEYAMEAASQSGTCVGLLAKNGVLLATE-RSVDKLMDTSIPVPRI 64
            |:|.:||||||||||||||||||||||...:|||:|:||.:|||||.| |::.||:|......:|
Human     1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKI 65

  Fly    65 SWLNENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQYGGKRPF 129
            ..|||::||...|.|:|.|||.|:||:|||:|...:.|.||||||||.||||||||||:||||||
Human    66 YKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPF 130

  Fly   130 GVSFLYMGWDCRFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPSVEEAKDV 194
            |||.||:|||..:|||||||||||||.||||||||..|.||:.||::: :.:|.:  :::.|..:
Human   131 GVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQD-YKEGEM--TLKSALAL 192

  Fly   195 AIKVMGMTLGRDSLTPEKLEIAFVQRYGNTTVFHILEKNEIHRLIERN 242
            ||||:..|:....|:.||:|||.:.|....||..:|::.|:.:||:::
Human   193 AIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKH 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	138/240 (58%)
		Ntn_hydrolase	3..218	CDD:294319	130/215 (60%)
PSMA4	NP_001096137.1	proteasome_alpha_type_4	3..216	CDD:239721	130/215 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..261		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158455
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S260
OMA	1	1.010	-	-		QHG54118
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003645
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2516
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.770