DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3T and ctsv

DIOPT Version :9

Sequence 1:	NP_651843.1	Gene:	Prosalpha3T / 43679	FlyBaseID:	FBgn0261395	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001004869.1	Gene:	ctsv / 448179	XenbaseID:	XB-GENE-966214	Length:	335	Species:	Xenopus tropicalis

Alignment Length:	185	Identity:	36/185 - (19%)
Similarity:	61/185 - (32%)	Gaps:	54/185 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 QYQFNFGEMIPCEQLVTNLCDIKQA----------------YTQYGGKRPFGVSFLYMGWD---C 140
            |:..|.|:||...:  .||.|..:|                |.:..|......|:.|...|   |
Frog   150 QHYRNTGKMISLSE--QNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQEC 212

  Fly   141 RFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPSVE---------------- 189
            .:       ||  ||:....|.....:..:.:.|...:.|.|.||.:|:
Frog   213 HY-------DP--NYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYE 268

  Fly   190 -----EAKDVAIKVMGMTLGRDSLTPEKLEI---AFVQRYGNTTVFHILEKNEIH 236
                 |..|..:.|:|.....:....:|..|   ::.:::||....:|.:....|
Frog   269 PECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNH 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	36/185 (19%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:294319	32/165 (19%)
ctsv	NP_001004869.1	Inhibitor_I29	29..87	CDD:214853
ctsv	NP_001004869.1	Peptidase_C1	115..334	CDD:306594	36/185 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900