DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3T and Prosalpha3

DIOPT Version :9

Sequence 1:	NP_651843.1	Gene:	Prosalpha3T / 43679	FlyBaseID:	FBgn0261395	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_476691.1	Gene:	Prosalpha3 / 37378	FlyBaseID:	FBgn0261394	Length:	264	Species:	Drosophila melanogaster

Alignment Length:	242	Identity:	155/242 - (64%)
Similarity:	199/242 - (82%)	Gaps:	1/242 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARFFDSRTTIFSPEGRLYQVEYAMEAASQSGTCVGLLAKNGVLLATE-RSVDKLMDTSIPVPRI 64
            |||.:||||||||||||||||||||||.|.:|||:|:||::|:|||.| ||.:||:|::||..:|
  Fly     1 MARRYDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEKI 65

  Fly    65 SWLNENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQYGGKRPF 129
            ..||:|:.|...|.|:|.|||.::||:|||:|||::||:|||||||::|||||||||||||||||
  Fly    66 YRLNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPF 130

  Fly   130 GVSFLYMGWDCRFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPSVEEAKDV 194
            |||.||||||.::|:|||||||||||.||||||||...|||:.||::||..|..|..::.:|||:
  Fly   131 GVSLLYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDL 195

  Fly   195 AIKVMGMTLGRDSLTPEKLEIAFVQRYGNTTVFHILEKNEIHRLIER 241
            ||||:.|||....|||||:|:|.:||..|.||:.:|||.::.:|||:
  Fly   196 AIKVLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEK 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	154/240 (64%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:294319	142/215 (66%)
Prosalpha3	NP_476691.1	PTZ00246	1..245	CDD:173491	155/242 (64%)
Prosalpha3	NP_476691.1	proteasome_alpha_type_4	3..219	CDD:239721	142/215 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468239
Domainoid	1	1.000	210	1.000	Domainoid score	I795
eggNOG	1	0.900	-	-		E1_COG0638
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I898
Isobase	1	0.950	-	0	Normalized mean entropy	S260
OMA	1	1.010	-	-		QHG54118
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003645
OrthoInspector	1	1.000	-	-		mtm1202
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2516
	12	11.860