DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3T and Psma4

DIOPT Version :9

Sequence 1:	NP_651843.1	Gene:	Prosalpha3T / 43679	FlyBaseID:	FBgn0261395	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_058977.1	Gene:	Psma4 / 29671	RGDID:	61846	Length:	261	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	137/243 - (56%)
Similarity:	182/243 - (74%)	Gaps:	4/243 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARFFDSRTTIFSPEGRLYQVEYAMEAASQSGTCVGLLAKNGVLLATE-RSVDKLMDTSIPVPRI 64
            |:|.:||||||||||||||||||||||...:|||:|:||.:|||||.| |::.||:|......:|
  Rat     1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKI 65

  Fly    65 SWLNENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQYGGKRPF 129
            ..|||::||...|.|:|.|||.|:||:|||:|...:.|.||||||||.||||||||||:||||||
  Rat    66 YKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPF 130

  Fly   130 GVSFLYMGWDCRFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPSVEEAKDV 194
            |||.||:|||..:|||||||||||||.||||||||..|.||:.||::: :.:|.:  :::.|..:
  Rat   131 GVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQD-YKEGEM--TLKSALAL 192

  Fly   195 AIKVMGMTLGRDSLTPEKLEIAFVQRYGNTTVFHILEKNEIHRLIERN 242
            |:||:..|:....|:.||:|||.:.|....||..:|::.|:.:||:::
  Rat   193 AVKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKH 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	137/240 (57%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:294319	129/215 (60%)
Psma4	NP_058977.1	proteasome_alpha_type_4	3..216	CDD:239721	129/215 (60%)
Psma4	NP_058977.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..261		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352455
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54118
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003645
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2516
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.820