DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3T and Psmb7

DIOPT Version :9

Sequence 1:	NP_651843.1	Gene:	Prosalpha3T / 43679	FlyBaseID:	FBgn0261395	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_035317.1	Gene:	Psmb7 / 19177	MGIID:	107637	Length:	277	Species:	Mus musculus

Alignment Length:	213	Identity:	45/213 - (21%)
Similarity:	93/213 - (43%)	Gaps:	22/213 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FSPEGRLYQVEYAMEAASQSGTCV-GLLAKNGVLL-ATERSVDKLMDTSIPVPRISWLNENIACC 74
            |:.:|      :.:..|.::||.: |::.|:|::| |..|:.:.::.......:|.:::.||.||
Mouse    29 FAKKG------FKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCC 87

  Fly    75 ATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQYGGKRPFGVSFLYMGWD 139
            ..|..||.::....:....:.:....|.:   .::||....:||...:|.|.  .|.:.:..|.|
Mouse    88 GAGTAADTDMTTQLISSNLELHSLTTGRL---PRVVTANRMLKQMLFRYQGY--IGAALVLGGVD 147

  Fly   140 CRFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPSV--EEAKDVAIKVMGMT 202
            .. |..||...|.|:........:|..|.|||.:.:.:.      .|.:  ||||.:..:.:...
Mouse   148 VT-GPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKF------RPDMEEEEAKKLVSEAIAAG 205

  Fly   203 LGRDSLTPEKLEIAFVQR 220
            :..|..:...:::..:.:
Mouse   206 IFNDLGSGSNIDLCVISK 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	45/213 (21%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:294319	45/209 (22%)
Psmb7	NP_035317.1	PRE1	41..225	CDD:223711	42/195 (22%)
		proteasome_beta_type_7	44..232	CDD:239732	41/192 (21%)
		Pr_beta_C	236..271	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900