DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha3T and AgaP_AGAP008837

DIOPT Version :9

Sequence 1:	NP_651843.1	Gene:	Prosalpha3T / 43679	FlyBaseID:	FBgn0261395	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_319581.3	Gene:	AgaP_AGAP008837 / 1279804	VectorBaseID:	AGAP008837	Length:	207	Species:	Anopheles gambiae

Alignment Length:	228	Identity:	50/228 - (21%)
Similarity:	84/228 - (36%)	Gaps:	72/228 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TCVGLLAKNGVLLATE----RSVDKLMDTSIPVPRISWLNENIACCATGNTAD---------GNV 84
            |.:|:...:.|:||.:    .|:..|.|....:.::|   :|:.....|...|         .|:
Mosquito     5 TLMGIRGPDFVMLAADCTHAHSIMVLKDDEDKILKVS---DNLMLATMGEAGDRVQFTEYISKNI 66

  Fly    85 LVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQYGGKRPFGVSFLYMGWDCRFGFQLYQS 149
            |:.::|     ..:..|..........||.|..::.|      |:.|:.|..|:|...|.||:
Mosquito    67 LLYRMR-----NGYELGPKAAAHFTRRNLADYLRSRT------PYHVNLLVGGYDEVDGPQLH-- 118

  Fly   150 DPSGNYSGWKATCIGRKSGA----AM------------EMLQK---ELFSKGYVS---------P 186
                 |..:.|..:..|.||    .|            ::.||   |:|.||...         |
Mosquito   119 -----YIDYLANSLPVKHGAHGYGGMFVNSIFDRYHHDKITQKEAYEIFRKGVTEIHKRLILNLP 178

  Fly   187 SVEEA---KDVAIKVMGMTLGRDSLTPEKLEIA 216
            :.:.|   || .:|.:      |.:||:.|:.|
Mosquito   179 NFKVAVIDKD-GVKYL------DDITPDSLKQA 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha3T	NP_651843.1	PTZ00246	1..241	CDD:173491	50/228 (22%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:294319	50/228 (22%)
AgaP_AGAP008837	XP_319581.3	PRE1	1..196	CDD:223711	46/218 (21%)
AgaP_AGAP008837	XP_319581.3	proteasome_beta_type_2	3..195	CDD:239727	45/217 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900