Protein Alignment CG11318 and ADGRE3

DIOPT Version :9

• Sequence 1: NP_651842.3
• Gene: CG11318 / 43678
• FlyBaseID: FBgn0039818
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: NP_115960.2
• Gene: ADGRE3 / 84658
• HGNCID: 23647
• Length: 652
• Species: Homo sapiens
• Alignment Length: 691
• Identity: 155/691 - (22%)
• Similarity: 266/691 - (38%)
• Gaps: 186/691 - (26%)

  Fly   133 CLRRFREHTISGDLNSLHDDVLEGRRRTNDTQGRREMTGIMRNMFRQRGGNLLPADVHMTGQMFG 197
            |:..:|.|:.:...::.:::..:....:..|:||:|:..|:...           :..:|.|
Human    96 CVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEGRKELQKIVDKF-----------ESLLTNQ--- 146

  Fly   198 ALMQQDKDATVSVDLVSVCKEIMSCDSKVLRLSAQLNATNSLLSQFESYMDALPEQLVPKDRCGK 262
            .|.:.:....:|....::.:::   :||||..:.:......|..|.:|.  |:..|.: .|.|
Human   147 TLWRTEGRQEISSTATTILRDV---ESKVLETALKDPEQKVLKIQNDSV--AIETQAI-TDNC-- 203

  Fly   263 VVAKPTSDEAETATTGVETYNFSDIGVQALITGNISVFFANPECDRITGLAIFSAPGDQRKTSAS 327
                  |:|.:|....|: .|..||....:|                        .||.:..||
Human   204 ------SEERKTFNLNVQ-MNSMDIRCSDII------------------------QGDTQGPSA- 236

  Fly   328 GFWYRFIRFSEDLAKVKEESNLETAAFLPENLWRQVKSRGATYLIFKVYAHDALFVETSLQRTRK 392
               ..||.:|       ...|:..|.|..|     :..:...||
Human   237 ---IAFISYS-------SLGNIINATFFEE-----MDKKDQVYL--------------------- 265

  Fly   393 PRSKVISISIPGLRSNYLSLPLPFLLRNENLRNPDSKAFSIGSGCGYWNY----ETWSTEG---V 450
             .|:|:|.:|...|:..||..:....::..:.....|.|     |.||..    ..||.:|   :
Human   266 -NSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVF-----CVYWKSTGQGSQWSRDGCFLI 324

  Fly   451 STESSSDLLKDAIIECHTNHLTQFAFLVGGSYRANDLGEEILITPINEKVLDIISIVGCSLSLLG 515
            ....|..:       |:.:||:.||.|:.            |.:...:.||.:|:.||.|:|||.
Human   325 HVNKSHTM-------CNCSHLSSFAVLMA------------LTSQEEDPVLTVITYVGLSVSLLC 370

  Fly   516 ILGIFLTAALFKSWRSQASTKVLLHLCLAMCLQMMLFVFLNTDDVSEALVVNGNTVRCVALGAAM 580
            :|...||..|.|:.|   :|...|||.|::||.:...:||...|.:|..|:      |..:..|:
Human   371 LLLAALTFLLCKAIR---NTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVL------CSIIAGAL 426

  Fly   581 QYSILVLFSWMLI--IAFLQFQRYVTVIGIERPPRYILKAAIVAWLL-PL---VPTLLVALIDPD 639
            .|..|..|:|||:  :......|.:||:......|      ::.|:: |:   ||.:.||:
Human   427 HYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINR------LMKWIMFPVGYGVPAVTVAI---- 481

  Fly   640 SYVPSAAQLSTDTGICYPSGY------------GLIFGVVLPVTLITVCNLVIFVYVFYSISHSL 692
                |||.        :|..|            |.::..:.||..|...|||:|:.||:.:...|
Human   482 ----SAAS--------WPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKL 534

  Fly   693 SQ-----SIHKNEKKMVVKQIRLSIMLFFLLGLTWIFGIFAFMQAGVAFSYLFCITATMQGFVMF 752
            |.     |..:|.:.:..|    :....|:||.||..|:.....|....:|||.|..::|||.:|
Human   535 SSLNSEVSTIQNTRMLAFK----ATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIF 595

  Fly   753 IYFVLLDSTNRRLWVGLICPTKMELDVQKRTTELQSMTTSS 793
            :.:.||....::.:      .|...::.|..:|.::.|.||
Human   596 LVYCLLSQQVQKQY------QKWFREIVKSKSESETYTLSS 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11318	NP_651842.3	GPS	437..475	CDD:280071	10/44 (23%)
		7tm_4	500..750	CDD:304433	78/272 (29%)
ADGRE3	NP_115960.2	EGF_CA	67..104	CDD:238011	2/7 (29%)
		GPS	304..344	CDD:280071	12/46 (26%)
		7tm_4	353..594	CDD:304433	79/275 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810