Protein Alignment CG11318 and Adgrf4

DIOPT Version :9

• Sequence 1: NP_651842.3
• Gene: CG11318 / 43678
• FlyBaseID: FBgn0039818
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: NP_001276428.1
• Gene: Adgrf4 / 78249
• MGIID: 1925499
• Length: 698
• Species: Mus musculus
• Alignment Length: 577
• Identity: 123/577 - (21%)
• Similarity: 206/577 - (35%)
• Gaps: 199/577 - (34%)

  Fly   320 DQRKTSA--SGFWYRFIRFSEDLAKVKEESNLETAAFLPENLWRQVKSRGATYLIFKVYAH---- 378
            |..|:||  ||    .|.|..:|.| ...|||:|:.......|:::|:.|      ||..|
Mouse   147 DAVKSSAVTSG----NIAFIVELLK-NISSNLQTSGIHDNVNWKKMKNYG------KVANHILGP 200

  Fly   379 ---------------------------------------DALFVET------------------- 385
                                                   |.||::|
Mouse   201 TAISNWAFIANKNASSDLLESVNSFAKKLQIQGKSESIVDELFIQTKGSRISHSSSEHSLSLSVP 265

  Fly   386 -----------------SLQRTRKPRSKVISISIPGL--------RSN----------YLSLPLP 415
                             :||......|:.|.::.|.|        |.|          .|||.||
Mouse   266 RYNATEDVLVVIEIPRQALQELSFNASQAIVVAFPTLGAILKEVHRPNTNLQKPIDDLILSLVLP 330

  Fly   416 FLLRNENLRNPD--SKAFSIGSGCGYWNYETWSTEGVSTESSSDLLKD--AIIEC---HTNHLTQ 473
            ..| ||.:...|  :|:.|..|.|..|:..|    |...||...::.|  :.::|   ||..:|.
Mouse   331 EGL-NEIILTFDKINKSQSTSSQCVSWDPAT----GQWDESPCTVMSDINSTVKCRCRHTKAVTS 390

  Fly   474 FAFLVGGSYRANDLGEEILITPINEKVLDIISIVGCSLSLLGILGIFLTAALFKSWRSQASTKV- 537
            |:.|:...             |:...:|:.|:.:|.|:|:..::...:..|:.  |.....|::
Mouse   391 FSILMSSK-------------PVKNTILNHITFIGLSISIFSLVLCLVIEAIV--WSRVVVTEIS 440

  Fly   538 -LLHLCLAMCLQMMLFVFLNTDDVSEALVVNGN---TVR-----CVALGAAMQYSILVLFSWMLI 593
             :.|:|:     :.:.|.|.|.:|  ..::..|   .|:     |||:.....:..|.||.|||
Mouse   441 YMRHVCI-----VNIAVSLLTANV--WFIIGSNFSANVQEDHKWCVAVTFLCHFFFLSLFFWML- 497

  Fly   594 IAFLQFQRYVTVIGIERPPRYILKAAIVA------WLLPLVPTLLVALIDPDSYVPSAAQLSTDT 652
                 |:..:.|.||....|.::|:.::|      :..|||..::...:             |:.
Mouse   498 -----FKALLIVYGILVVFRRMMKSRMMAIGFAIGYGCPLVIAVITVTV-------------TEP 544

  Fly   653 GICYPSGY-------------GLIFGVVLPVTLITVCNLVIFVYVFYSISHSLSQSIHKNEKKMV 704
            |    .||             ..:|...:|...|...||::.:.|..:....|..|....:..:|
Mouse   545 G----EGYTRKDACWLNWNQTKALFAFAIPALAIVAVNLLVVLAVAINTQRPLIGSSKSQDMAIV 605

  Fly   705 VKQIRLSIMLFFLLGLTWIFGIFAFMQAGV--AFSYLFCITATMQGFVMFIYFVLLD 759
            .:..:...:|..||||||.||:...:: ||  .|..:|.:....|||.:.::..::|
Mouse   606 FRISKNVAILTPLLGLTWGFGLTTLLE-GVHLVFHIIFALLNAFQGFFILLFGTIMD 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11318	NP_651842.3	GPS	437..475	CDD:280071	11/42 (26%)
		7tm_4	500..750	CDD:304433	63/280 (23%)
Adgrf4	NP_001276428.1	GPS	351..394	CDD:366827	13/46 (28%)
		7tm_GPCRs	402..669	CDD:391938	65/293 (22%)
		TM helix 1	405..429	CDD:341315	5/23 (22%)
		TM helix 2	444..465	CDD:341315	6/27 (22%)
		TM helix 3	479..501	CDD:341315	9/27 (33%)
		TM helix 4	522..538	CDD:341315	3/15 (20%)
		TM helix 5	560..583	CDD:341315	5/22 (23%)
		TM helix 6	606..631	CDD:341315	9/24 (38%)
		TM helix 7	636..661	CDD:341315	5/24 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810