Protein Alignment Mayo and mthl5

DIOPT Version :10

• Sequence 1: NP_651842.3
• Gene: Mayo / 43678
• FlyBaseID: FBgn0039818
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Alignment Length: 395
• Identity: 82/395 - (20%)
• Similarity: 138/395 - (34%)
• Gaps: 114/395 - (28%)

  Fly   431 FSIG-SGCGYWNYETWSTEGVSTESSSD---LLKDAIIECHTN--------HLTQFAFL--VGGS 481
            |.|| ..||  :.:.|.....:  .|||   ||.|..:..:||        |..|..:.  :.||
  Fly   106 FVIGIPNCG--SMQMWPIYHYA--GSSDKLVLLDDGRLRHYTNAENEAEERHGIQSDYEEDIAGS 166

  Fly   482 ----YRANDLG-------------EEILITPI---------------NEKVLDIISIVGCSLSLL 514
                |...|.|             |.:|...|               ..|:|:.| ..|.||.:|
  Fly   167 LEPLYHDYDKGLYCIDKATSSTGEENVLFANICLARKEIKWSDSNFLLRKILNPI-FHGISLVIL 230

  Fly   515 GILGI--FLTAALFKSWRSQASTKVLLHLCLAMCL---QMMLFVFLNTDDVSEALVVNGNTVRCV 574
            .::.|  |:...|.:.......|.:      ||||   |....|.:.|:..|....:..:.:.|
  Fly   231 LVIAIIYFILPTLSRDLVGNIVTTI------AMCLMVSQAADLVRIFTELTSHVSFIVADIILC- 288

  Fly   575 ALGAAMQYSILVLFSWMLIIAFL---QFQRYVTVIGIERPPRYILKAAIVAWLLPLVPTLLVA-- 634
                   :|:|..|.|:....|.   .|:.....:.:....:|...:| .||........|..
  Fly   289 -------FSLLAAFFWLNSFGFYIWKTFRSRNVFLRVTDGRKYCYYSA-YAWGCTATMAALAVFA 345

  Fly   635 --LIDPDSYVPSAAQLSTDT----GICYPSGYGLIFGVVLPVTLITVCNLVIFV---------YV 684
              .:|.:||.........:|    |||       ||  ..|:....:.|:..:|         .|
  Fly   346 HFFLDAESYKQEHMVGEQETIGWLGIC-------IF--FAPIACTILVNIFFYVTTRKLINRRTV 401

  Fly   685 FYSISHSLSQSIHKNEKKMVVKQIRLSIMLFFLLGLTWIFGIFAFMQ-AGVAFSYLFCITATMQG 748
            :..|:|.|..:.           |..|:|| .::.:.|:|.|.:::| .|:.:::: .:.|....
  Fly   402 YGRIAHKLKANF-----------IMFSLML-LVMSIAWLFLIMSWLQMEGLLYAHI-VVNALQTP 453

  Fly   749 FVMFI 753
            .:::|
  Fly   454 LLLYI 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mayo	NP_651842.3	7tmB2_Adhesion	498..766	CDD:320168	58/282 (21%)
		TM helix 1	500..525	CDD:320168	8/26 (31%)
		TM helix 2	535..557	CDD:320168	7/24 (29%)
		TM helix 3	574..600	CDD:320168	5/28 (18%)
		TM helix 4	615..635	CDD:320168	4/23 (17%)
		TM helix 5	659..688	CDD:320168	6/37 (16%)
		TM helix 6	704..730	CDD:320168	7/25 (28%)
		TM helix 7	734..759	CDD:320168	2/20 (10%)
mthl5	NP_001287291.1	7tmB3_Methuselah-like	215..474	CDD:410632	58/282 (21%)
		TM helix 1	215..239	CDD:410632	8/24 (33%)
		TM helix 2	249..271	CDD:410632	7/27 (26%)
		TM helix 3	281..308	CDD:410632	6/34 (18%)
		TM helix 4	324..344	CDD:410632	5/20 (25%)
		TM helix 5	371..396	CDD:410632	7/33 (21%)
		TM helix 6	409..435	CDD:410632	8/37 (22%)
		TM helix 7	438..463	CDD:410632	3/22 (14%)