DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11318 and Adgrf3

DIOPT Version :9

Sequence 1:NP_651842.3 Gene:CG11318 / 43678 FlyBaseID:FBgn0039818 Length:802 Species:Drosophila melanogaster
Sequence 2:XP_006535799.1 Gene:Adgrf3 / 381628 MGIID:2685887 Length:1059 Species:Mus musculus


Alignment Length:638 Identity:129/638 - (20%)
Similarity:225/638 - (35%) Gaps:139/638 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   153 VLEGRRRTNDTQGR--REMTGIMRNMFRQRGGNLLPAD----VHMTGQMFGALMQQDKDATVSV- 210
            :|||       ||:  .|:..|:..:..|.|....|:|    :|....:...:.:...:.|.|. 
Mouse   414 LLEG-------QGKPYEEVPWILSELQEQVGVASTPSDLWEMLHTVTLLAKVVAETSTELTGSAL 471

  Fly   211 -DLVSVCKEIMSCDSKVLRLSAQLNATNSLLSQFESYMDALPEQLVPKDRCGKVVAKPTSDEAET 274
             ||::...:|:..:...|...||.... |:.|.|...::.|...|.|:.                
Mouse   472 KDLLTTTDKILDANISALWTLAQAQEP-SMGSDFLKAVETLVHSLRPQQ---------------- 519

  Fly   275 ATTGVETYNFSDIGVQALITGNISVFFANPECDRITGLAIFSAPGDQRKTSASGFWYRFIRFSED 339
                 ..::||...|  |:...:              |...|.||.|...|........|.:...
Mouse   520 -----HPFSFSSANV--LLQSQL--------------LRHSSPPGYQMSFSTWPLLQARIPWHSL 563

  Fly   340 LAKVKEESNLETAAFLPENLWRQVKSRGATYLIFKVYAHDALFVETSLQRTRKPRSKVISISIPG 404
            ...|...:|:...:.:.:.|..::.|.....|....|....|.:             |:||:..|
Mouse   564 APLVHSGTNVSITSLVLQKLDYRLPSNYTQGLWNTPYTTPGLIL-------------VVSITADG 615

  Fly   405 LRSNYLSLPLPFLLRNENLRNPDSKAFSIGSGCGYWNYET------WSTEGVSTESSSDLLKDAI 463
            .......:.:.:...|..|.            |.:|::..      ||.||....:::    .:|
Mouse   616 QAFTQAEVIMDYEDMNGTLH------------CVFWDHRVFQGQGGWSDEGCEVHAAN----ASI 664

  Fly   464 IECHTNHLTQFAFLVGGSYRANDLGEEILITPINEKVLDIISIVGCSLSLLGILGIFLTAALFKS 528
            .:|...|||.|:.|:...            |......||::|.||...|:|.:|.......|.  
Mouse   665 TQCICQHLTAFSILMSQH------------TVPENPTLDLLSQVGTGASVLALLVCLAIYGLV-- 715

  Fly   529 WRSQASTKVLL--HLCL---AMCLQMMLFVFLNTDDVSEALVVNGNTVRCVALGAAMQYSILVLF 588
            ||.....||..  |..|   .:||.:....||.    |..|....:::.|:.......:..|..|
Mouse   716 WRVVVRNKVAFFRHTTLFNMVICLLVADTCFLG----SPFLPSGYHSLICLVTAFLCHFFYLATF 776

  Fly   589 SWM----------LIIAFLQFQRYVTVIGIERPPRYILKAAIVAWLLPLVPTLLVALIDPDSYVP 643
            .||          |:..|.|..::| |:.:         ..::.:|.||.    .|.:....|:|
Mouse   777 FWMLAQALVLAHQLLFVFHQLSKHV-VLSL---------MVMLGYLCPLG----FAGVTLGLYLP 827

  Fly   644 SAAQLSTDTGICYPSGYG-LIFGVVLPV-TLITVCNLVIFVYVFYSISHSLSQSIHKNEKKMVVK 706
            ....|.  .|.|:.:|.| :::....|| .::.|..||:.:.|...:..|||:.....:::.:|.
Mouse   828 QRKYLW--EGKCFLNGGGVMLYSFSEPVLAIVGVNGLVLVIAVLKLLRPSLSEGPTVEKRQALVG 890

  Fly   707 QIRLSIMLFFLLGLTWIFGIFAFMQAGVAFSYLFCITATMQGFVMFIYFVLLD 759
            .::..::|..:.||||..|:.......:...|.|.|..::||..:.::..|.|
Mouse   891 VLKALLILTPIFGLTWGLGVATLFDGSIVSHYAFSILNSLQGVFILVFGCLTD 943

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11318NP_651842.3 GPS 437..475 CDD:280071 11/43 (26%)
7tm_4 500..750 CDD:304433 63/266 (24%)
Adgrf3XP_006535799.1 HRM 352..398 CDD:367186
GPS 635..678 CDD:366827 12/58 (21%)
7tm_GPCRs 688..954 CDD:391938 65/278 (23%)
TM helix 1 689..714 CDD:341315 8/24 (33%)
TM helix 2 729..751 CDD:341315 7/25 (28%)
TM helix 3 762..789 CDD:341315 4/26 (15%)
TM helix 4 803..823 CDD:341315 4/32 (13%)
TM helix 5 842..871 CDD:341315 7/28 (25%)
TM helix 6 887..914 CDD:341315 7/26 (27%)
TM helix 7 918..943 CDD:341315 6/24 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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