DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11318 and Adgrg5

DIOPT Version :9

Sequence 1:	NP_651842.3	Gene:	CG11318 / 43678	FlyBaseID:	FBgn0039818	Length:	802	Species:	Drosophila melanogaster
Sequence 2:	XP_008770523.1	Gene:	Adgrg5 / 307645	RGDID:	1305559	Length:	564	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	88/372 - (23%)
Similarity:	142/372 - (38%)	Gaps:	81/372 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 MDALPEQLVPKDRCGKVVAKPTSD--------EAETATTGVETYNFSDIGVQALITGNISVFFAN 303
            ::.|||.|....|..:.:.:..|.        |..........:|.:      |.|.:|......
  Rat    21 VETLPEILNLMKRLERPIGRALSSRVRFIHHLEQMLLNASFHGHNLT------LQTNSIQSLVFK 79

  Fly   304 PECDRITGLAIFSAPGDQRKTSASGFWY-RFIRFSEDLAKVKEESNLETAAFLPENLWRQVKSRG 367
            ..|. ..||::.||    ..|:.|..|. ..::|..:|.|        .|.         |.||.
  Rat    80 LSCG-FPGLSLSSA----TLTNVSQAWAPHAMQFPAELTK--------NAC---------VTSRP 122

  Fly   368 ATYLIFKVYAHDALFVETSLQRTRKPRSKVISISIPGLRSNYLSLPLPFLLRNENL---RNPDSK 429
            |...:..||    .|.....|..|  .|.:::..:.|.:.::  .|:..|.|..|:   .|...:
  Rat   123 AELRLICVY----FFTAHLFQDDR--NSSLLNNYVLGAQLDH--RPVNNLQRPVNISFWHNRSLE 179

  Fly   430 AFSIGSGCGYW-------NYETWSTEGVSTESSSDLLKDAIIECHTNHLTQFAFLVGGSYRANDL 487
            .:::  .|.:|       ::..||.:|..||..|    ...:.||.||||.||.|:..|
  Rat   180 GYTV--TCVFWKEGAGKHSWGAWSPKGCYTEQPS----PTQVLCHCNHLTYFAVLMQLS------ 232

  Fly   488 GEEI---LITPINEKVLDIISIVGCSLSLLGILGIFLTAALFKSWRSQASTKVLLHLCLAMCLQM 549
            |:.:   |.||     |:.||:||||:|::..|   ||..|....|..:.:...:||.|...:.:
  Rat   233 GDPVPTELQTP-----LEYISLVGCSISIVASL---LTILLNAHSRKLSDSTTRIHLNLNGSVLL 289

  Fly   550 MLFVFLNTDDVSEALVVNGNTVRCVALGAAMQYSILVLFSWMLIIAF 596
            :...||.:..:....|...   .|..|.|.:.|::|...:||.:..|
  Rat   290 LNITFLLSSQMVPPTVPRS---VCTVLAATLHYALLSSLTWMGVEGF 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11318	NP_651842.3	GPS	437..475	CDD:280071	14/44 (32%)
CG11318	NP_651842.3	7tm_4	500..750	CDD:304433	27/97 (28%)
Adgrg5	XP_008770523.1	GPS	184..228	CDD:396408	16/47 (34%)
		7tm_GPCRs	243..>349	CDD:421689	28/102 (27%)
		TM helix 1	243..268	CDD:410628	13/32 (41%)
		TM helix 2	277..299	CDD:410628	5/21 (24%)
		TM helix 3	311..338	CDD:410628	7/23 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I6879
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12011
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910