Protein Alignment Mayo and Adgrg3

DIOPT Version :10

• Sequence 1: NP_651842.3
• Gene: Mayo / 43678
• FlyBaseID: FBgn0039818
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: XP_038954076.1
• Gene: Adgrg3 / 291854
• RGDID: 1305674
• Length: 574
• Species: Rattus norvegicus
• Alignment Length: 421
• Identity: 94/421 - (22%)
• Similarity: 175/421 - (41%)
• Gaps: 90/421 - (21%)

  Fly   395 SKVISISIPGLRSNYLSLPLPFLLRNENLRNPDSKAFSIGSGCGYWNYE--TWSTEGVSTESSSD 457
            ::::.:|:..:.:..||.|:.....::: ::|     ::...|.:|:..  .|.:.|.|||..
  Rat   209 NRMVGLSVGQMHATGLSEPVEITFSHQH-QSP-----NVILTCVFWDMAKGDWDSHGCSTEPG-- 265

  Fly   458 LLKDAIIECHTNHLTQFAFLVGGSYRANDLGEEILITPINEKVLDIISIVGCSLSLLGILGIFL- 521
               |....|..:|||.||.|:..:           :.....:.|..||..|.::|:     |||
  Rat   266 ---DGRTVCRCDHLTFFALLLRPT-----------LDQATARTLTRISQAGSAVSM-----IFLA 311

  Fly   522 -TAALFKSWR-------SQASTKVLLHLCLAMCLQMMLFVFL-NTDDVSEALVVNGNTVRCVALG 577
             |..|:.::|       |:.:.|:  |:.|:..|.::...|| |....|:     |....|....
  Rat   312 FTMVLYVAFRFSLQRFKSEDAPKI--HMALSTSLFLLNLTFLINVGSGSQ-----GPPASCWVRA 369

  Fly   578 AAMQYSILVLFSWMLIIAFLQFQRYVTVIGIERP--PRYILKAAIVAWLLPLVPTLLVALIDPDS 640
            |...|.:|.:|:||.:.|   |..|:.||.:...  ..|.||.:::.|.||::  :::.:...:|
  Rat   370 AIFHYFLLCVFTWMGLEA---FHLYLLVIKVFNTYFGHYFLKLSLLGWGLPVL--IVIGVGSSNS 429

  Fly   641 ---YVPSAAQLSTDTGICY----PSGYGLIFGVVLPVTLITVCNLVIFVYVFYSISHSLSQSIHK 698
               |.....:..|...:|:    |:.|..:.|..|...|.....|.:..:..:::....:.....
  Rat   430 YGVYTIRDQENRTSLELCWFQKEPALYATVHGYFLVTFLFGAVVLAMVAWKIFTLPSVTAGKGQG 494

  Fly   699 NEKKMVVKQIRLSIMLFFLLGLTWIFGIFAFMQAGVAFSYLFCITATMQGFVMFIYFVLLDSTNR 763
            ...|.|:..:.||    .|:|:||  |:......|::..|:|.:..::||..:|.:|::
  Rat   495 QTWKSVLTVLGLS----SLVGMTW--GLAVLTPLGLSTVYIFTLLNSLQGLFIFCWFII------ 547

  Fly   764 RLWVGLICPTKMELDVQKRTTELQSMTTSST 794
                 |..||             ||.||||:
  Rat   548 -----LYFPT-------------QSTTTSSS 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mayo	NP_651842.3	7tmB2_Adhesion	498..766	CDD:320168	65/286 (23%)
		TM helix 1	500..525	CDD:320168	9/26 (35%)
		TM helix 2	535..557	CDD:320168	6/22 (27%)
		TM helix 3	574..600	CDD:320168	7/25 (28%)
		TM helix 4	615..635	CDD:320168	5/19 (26%)
		TM helix 5	659..688	CDD:320168	5/28 (18%)
		TM helix 6	704..730	CDD:320168	8/25 (32%)
		TM helix 7	734..759	CDD:320168	6/24 (25%)
Adgrg3	XP_038954076.1	GPS	244..282	CDD:460350	14/42 (33%)
		7tm_GPCRs	292..551	CDD:475119	66/292 (23%)
		TM helix 1	295..319	CDD:410628	10/28 (36%)
		TM helix 2	333..354	CDD:410628	6/22 (27%)
		TM helix 3	366..388	CDD:410628	7/24 (29%)
		TM helix 4	408..424	CDD:410628	4/17 (24%)
		TM helix 5	454..475	CDD:410628	4/20 (20%)
		TM helix 6	500..522	CDD:410628	8/27 (30%)
		TM helix 7	524..549	CDD:410628	6/35 (17%)