Protein Alignment CG11318 and ADGRG3

DIOPT Version :9

• Sequence 1: NP_651842.3
• Gene: CG11318 / 43678
• FlyBaseID: FBgn0039818
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: XP_005255899.1
• Gene: ADGRG3 / 222487
• HGNCID: 13728
• Length: 596
• Species: Homo sapiens
• Alignment Length: 616
• Identity: 127/616 - (20%)
• Similarity: 226/616 - (36%)
• Gaps: 190/616 - (30%)

  Fly   266 KPTSDEAETATTGVETYNFSDIGVQALI-------------TGNISVFFANPECDRI-TGLA--- 313
            |||.....|.......|:..::..:||.             ..|:..::.|.|...: .||.
Human    23 KPTEGPRNTCLGSNNMYDIFNLNDKALCFTKCRQSGSDSCNVENLQRYWLNYEAHLMKEGLTQKV 87

  Fly   314 ---IFSAPGDQRKTSASGFWYRFIRFSEDLAKV-----KEESNLETAAFLPENLWRQVK-SRGAT 369
               ...|......|:.:..:|    ||.:.::|     |:|........||::|:|.:. :|...
Human    88 NTPFLKALVQNLSTNTAEDFY----FSLEPSQVPRQVMKDEDKPPDRVRLPKSLFRSLPGNRSVV 148

  Fly   370 YLIFKV--YAHDALFVETSLQRTRKPR-----------SKVISISIPGLRSNYLSLPLPFLLRNE 421
            .|...:  .....||        :.||           ::::.:|:..:....|:.||..:..::
Human   149 RLAVTILDIGPGTLF--------KGPRLGLGDGSGVLNNRLVGLSVGQMHVTKLAEPLEIVFSHQ 205

  Fly   422 NLRNPDSKAFSIGSGCGYWNYE-----TWSTEGVSTESSSDLLKDAIIECHTNHLTQFAFLVGGS 481
              |.|.:...:    |.:|:..     .||:||.|||     ::.....|..:|||.||
Human   206 --RPPPNMTLT----CVFWDVTKGTTGDWSSEGCSTE-----VRPEGTVCCCDHLTFFA------ 253

  Fly   482 YRANDLGEEILITPINEK----VLDIISIVGCSLSLLG-----ILGIFLTAALFK---------- 527
                     :|:.|..::    :|..||..||.:|::.     ||..||:..|..
Human   254 ---------LLLRPTLDQSTVHILTRISQAGCGVSMIFLAFTIILYAFLSPGLGHGPHPQQAECD 309

  Fly   528 ---------------------------SW---------RSQASTKVLLHLCLAMCLQMMLFVFL- 555
                                       :|         :|:.:.|:  |:.|...|.::...||
Human   310 LPAGRIAGPCERGLERQEKLPPAPQGGAWHLRLSRERFKSEDAPKI--HVALGGSLFLLNLAFLV 372

  Fly   556 NTDDVSEALVVNGNTVRCVALGAAMQYSILVLFSWMLIIAF----LQFQRYVTVIGIERPPRYIL 616
            |....|:     |:...|.|.||...|.:|..|:||.:.||    |..:.:.|..|     .|.|
Human   373 NVGSGSK-----GSDAACWARGAVFHYFLLCAFTWMGLEAFHLYLLAVRVFNTYFG-----HYFL 427

  Fly   617 KAAIVAWLLPLVPTLLVALIDPDS---YVPSAAQLSTDTGICY-------------PSGYGLI-- 663
            |.::|.|.||.:  :::.....:|   |.....:..|...:|:             ..||.||
Human   428 KLSLVGWGLPAL--MVIGTGSANSYGLYTIRDRENRTSLELCWFREGTTMYALYITVHGYFLITF 490

  Fly   664 -FGVVLPVTLITVCNLVIFVYVFYSISHSLSQSIHKNEKKMVVKQIRLSIMLFFLLGLTWIFGIF 727
             ||:|:         |.:.|:..:::|.:.:.......:|.|:..:.||    .|:|:||  |:.
Human   491 LFGMVV---------LALVVWKIFTLSRATAVKERGKNRKKVLTLLGLS----SLVGVTW--GLA 540

  Fly   728 AFMQAGVAFSYLFCITATMQGFVMFIYFVLL 758
            .|...|::..|:|.:..::||..:..:|.:|
Human   541 IFTPLGLSTVYIFALFNSLQGVFICCWFTIL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11318	NP_651842.3	GPS	437..475	CDD:280071	13/42 (31%)
		7tm_4	500..750	CDD:304433	72/324 (22%)
ADGRG3	XP_005255899.1	GPS	213..255	CDD:280071	15/65 (23%)
		7tm_4	355..564	CDD:304433	58/237 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6566
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910