Protein Alignment CG11318 and ADGRF3

DIOPT Version :9

• Sequence 1: NP_651842.3
• Gene: CG11318 / 43678
• FlyBaseID: FBgn0039818
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: NP_001138640.1
• Gene: ADGRF3 / 165082
• HGNCID: 18989
• Length: 1079
• Species: Homo sapiens
• Alignment Length: 588
• Identity: 121/588 - (20%)
• Similarity: 207/588 - (35%)
• Gaps: 166/588 - (28%)

  Fly   318 PGDQRKTSASGFWYRFIRFSEDLAKVKEESNLETAAFLPEN---------------LWRQVKSR- 366
            ||...:.|:.......:...:.:|||..|:.::......:|               ||...::|
Human   512 PGQAAEASSPSDLLTLLSTMKYVAKVVAEARIQLDRRALKNLLIATDKVLDMDTRSLWTLAQARK 576

  Fly   367 ---GATYLIFKVYAHDALFVETSLQRTRKPRSKVISISIPGL-----------RSNY-LSLP--- 413
               |:|.|         |.||| |..:..|:....:.|:|.:           .::| :|.|
Human   577 PWAGSTLL---------LAVET-LACSLCPQDHPFAFSLPNVLLQSQLFGPTFPADYSISFPTRP 631

  Fly   414 ----------LPFLLRNEN--------LRNPD------------------------------SKA 430
                      |..|:||..        ||..|                              .:|
Human   632 PLQAQIPRHSLAPLVRNGTEISITSLVLRKLDHLLPSNYGQGLGDSLYATPGLVLVISIMAGDRA 696

  Fly   431 FSIGS------------GCGYWNYET------WSTEGVSTESSSDLLKDAIIECHTNHLTQFAFL 477
            ||.|.            .|.:|::..      ||.||...:.:|   .....:|...|||.|:.|
Human   697 FSQGEVIMDFGNTDGSPHCVFWDHSLFQGRGGWSKEGCQAQVAS---ASPTAQCLCQHLTAFSVL 758

  Fly   478 VGGSYRANDLGEEILITPINEKVLDIISIVGCSLSLLGI---LGIFLTAALFKSWRSQASTKV-- 537
            :...            |...|..|.:::.||...|:|.:   ||::     :..||.....|:
Human   759 MSPH------------TVPEEPALALLTQVGLGASILALLVCLGVY-----WLVWRVVVRNKISY 806

  Fly   538 LLHLCLAMCLQMMLFVFLNTDDV---SEALVVNGNTVRCVALGAAMQYSILVLFSWMLIIAFLQF 599
            ..|..|.    .|:|..|..|..   :..|.....:..|:|......:..|..|.|||..|.:..
Human   807 FRHAALL----NMVFCLLAADTCFLGAPFLSPGPRSPLCLAAAFLCHFLYLATFFWMLAQALVLA 867

  Fly   600 QRYVTVIGIERPPRYILKAAIVAWLLPLVPTLLVALIDPDSYVPSAAQLSTDTGICYPSGY-GLI 663
            .:.:.|.......|.:....::.:|.||.    :|.:....|:|....|.  .|.|:..|. |.:
Human   868 HQLLFVFHQLAKHRVLPLMVLLGYLCPLG----LAGVTLGLYLPQGQYLR--EGECWLDGKGGAL 926

  Fly   664 FGVVLPV-TLITVCNLVIFVYVFYSISHSLSQSIHKNEKKMVVKQIRLSIMLFFLLGLTWIFGIF 727
            :..|.|| .:|.|..||:.:.:...:..|||:.....:::.::..|:..::|..:.||||..|:.
Human   927 YTFVGPVLAIIGVNGLVLAMAMLKLLRPSLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLA 991

  Fly   728 AFM-QAGVAFSYLFCITATMQGFVMFIYFVLLDSTNRRLWVGLICPTKMELDVQKRTTELQSMTT 791
            ..: :......|:|.|..|:||..:.::..|:|             .|::..::||....|:  .
Human   992 TLLEEVSTVPHYIFTILNTLQGVFILLFGCLMD-------------RKIQEALRKRFCRAQA--P 1041

  Fly   792 SST 794
            |||
Human  1042 SST 1044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11318	NP_651842.3	GPS	437..475	CDD:280071	11/43 (26%)
		7tm_4	500..750	CDD:304433	61/260 (23%)
ADGRF3	NP_001138640.1	HRM	431..477	CDD:280888
		GPS	713..758	CDD:280071	12/47 (26%)
		7tm_4	770..1016	CDD:304433	61/260 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810