DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11318 and adgrg1

DIOPT Version :9

Sequence 1:	NP_651842.3	Gene:	CG11318 / 43678	FlyBaseID:	FBgn0039818	Length:	802	Species:	Drosophila melanogaster
Sequence 2:	XP_031756697.1	Gene:	adgrg1 / 100490972	XenbaseID:	XB-GENE-6041837	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	431	Identity:	100/431 - (23%)
Similarity:	179/431 - (41%)	Gaps:	89/431 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 KVISISIPGLRSNYLSLPLPFLLRNENLRNPDSKAFSIGSGCGYWNYET--WSTEGVSTESSSDL 458
            |||.:|:...:.:.|...:.|...:|.::...|..      |.:||..|  |||.|..|     .
Frog   304 KVIGVSVENTKVSNLCEDIMFTFEHEPVKTNFSPV------CVFWNESTDGWSTYGCKT-----F 357

  Fly   459 LKDAIIECHTNHLTQFAFLVGGSYRANDLGEEILITPINEKVLDIISIVGCSLSLLGILGIFLTA 523
            .|:...:|:.:|||.||.|:  .|.:..:.||.|::      |.:::..||::|.|..|......
Frog   358 PKENHTQCNCSHLTYFAVLM--QYSSQTISEEHLVS------LSVLTFAGCTISFLAALFTICWN 414

  Fly   524 ALFKSWRSQASTKVLLHLCLAMCLQMMLFV---FLNTDDVSEALVVNGNTVRCVALGAAMQYSIL 585
            ...:...|..:..:.::|..|:.|..:.|:   .|...|:...         |...|..:.::.|
Frog   415 CCTRKTHSNPTLNIHMNLLGAVLLLDLFFMSSAVLGAFDLPSV---------CKGSGMLLHFTQL 470

  Fly   586 VLFSWMLIIAFLQFQRYVTVIGIERPPRYILKAAIVAWLLPLVPTLLVALIDPDSY------VPS 644
            .:|:||.|..|..::..|.|  .:.......|.|::.|..|.:..|::.|||.|:|      |..
Frog   471 CMFTWMGIEGFNLYRLVVKV--FDSTSFATKKLAVIGWGFPALLVLVIFLIDFDNYGLYSINVDR 533

  Fly   645 AAQLSTDTGICYPS----------GYGLIFGVVLPVTLITVCNL--VIFVYVFYSISHSLSQSIH 697
            .:..::...||:.:          ||   ||:|    |:..|.:  |:.|.|.:.:.|:..::
Frog   534 PSSCNSRASICWLTEPLIHKVVNLGY---FGIV----LLFNCGMLTVMVVRVLHLMPHNRGEN-- 589

  Fly   698 KNEKKMVVKQIRLSIM-LFFLLGLTWIFGIFAFMQAGVAFSYLFCITATMQGFVMFIYFVLLDST 761
                    .|..:::: |..:|||.|....|:|....:...|||.|..::||..:|:::..|...
Frog   590 --------TQYCVTLLGLIVMLGLPWGIAFFSFGAVYLPVQYLFSILNSLQGLFIFLWYWALSHP 646

  Fly   762 NRRLWVGLICPTKMELDVQKRTTELQSMTTSSTNYNSRSHQ 802
            :                |:..:..|.|  :|:|..:.||.|
Frog   647 H----------------VKDPSRSLDS--SSATPASPRSDQ 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11318	NP_651842.3	GPS	437..475	CDD:280071	14/39 (36%)
CG11318	NP_651842.3	7tm_4	500..750	CDD:304433	61/271 (23%)
adgrg1	XP_031756697.1	PLL	61..>136	CDD:408370
		GPS	335..378	CDD:197639	18/55 (33%)
		7tm_GPCRs	392..643	CDD:421689	62/278 (22%)
		TM helix 1	392..416	CDD:410628	6/23 (26%)
		TM helix 2	426..448	CDD:410628	4/21 (19%)
		TM helix 3	459..486	CDD:410628	7/26 (27%)
		TM helix 4	498..518	CDD:410628	5/19 (26%)
		TM helix 5	549..578	CDD:410628	9/35 (26%)
		TM helix 6	588..614	CDD:410628	7/35 (20%)
		TM helix 7	619..643	CDD:410628	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7324
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000