DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11318 and adgrf1

DIOPT Version :9

Sequence 1:	NP_651842.3	Gene:	CG11318 / 43678	FlyBaseID:	FBgn0039818	Length:	802	Species:	Drosophila melanogaster
Sequence 2:	NP_001107298.1	Gene:	adgrf1 / 100135087	XenbaseID:	XB-GENE-6468452	Length:	1304	Species:	Xenopus tropicalis

Alignment Length:	723	Identity:	147/723 - (20%)
Similarity:	259/723 - (35%)	Gaps:	175/723 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 RATLHDVCLLRNGMP---------VTREC-----RVKDNRANWESTEHWDPVVCLRRFREHTISG 144
            :.||.....::.|.|         :|..|     .:..|::...::..|..||     .::.:..
Frog   639 KLTLRQQVEIKCGAPPGVGALGDIITVPCSSENINLTGNKSYTCTSTGWQAVV-----PDNCVLQ 698

  Fly   145 DLNSLHDDVLEGRRRTNDTQGRREMTGIMRNMFRQRGGNLLPADVHMTGQMFGALMQQDKDATVS 209
            .||.|..||             ..:||       ..|..:||..|                |.:|
Frog   699 VLNRLVSDV-------------PSLTG-------PGGAEILPVYV----------------ANLS 727

  Fly   210 VDLVSVCKEIMSCDSK---VLRLSAQLNATNSLLSQ--FESYMDALPEQLVPKDRCGKVVAKPTS 269
            ..:.:..:.|.|..|.   |:.:..|:..|...:..  .::::..:           .||...||
Frog   728 ATVTAEKENITSSPSNIVTVVNILQQVTTTTQTVQPDVMQNFLTTV-----------NVVVDDTS 781

  Fly   270 DEA-----ETATTGVETYNFSDIGVQALITGNISVFFANPECDRITGLAIFSAPGDQRKTSASGF 329
            ..|     .....|.:..|..:...:.|...|.|:...|....::.|:.          .::|..
Frog   782 KNAWNNMNNRTDRGTQLLNSVEQFARKLQIDNGSISIINNSNVQLAGII----------ANSSRS 836

  Fly   330 WYRFIRFSEDLAKVKEESNLETAAFLPENLWRQVKSRGATYLIFKVYA--HDALFVETSLQRTRK 392
            :.....||:.       :||..:..:.::....:::.  |.:|...||  .|.|...::......
Frog   837 YNESFNFSQG-------NNLTGSVLISKDSVSNMENN--TNIITIAYATLKDILLNTSTKVVNGL 892

  Fly   393 PRSKVISISIPGLRSNYLSLPLPFLLRNENLRNPDSKAFSIGSGCGYWNYET--WSTEGVSTESS 455
            ..:.|:|..:|   ||: .:.:.|...|:.|..|         ||.:||.||  |.:.|....::
Frog   893 VMTTVLSTQVP---SNF-KISMNFKKSNQTLNVP---------GCVFWNLETNNWDSTGCQGVNN 944

  Fly   456 SDLLKDAIIECHTNHLTQFAFLVGGSYRANDLGEEILITPINEKVLDIISIVGCSLSLLGILGIF 520
            ::     .:.|..:|||.|:.|:  ||:|           ::..|||.|:.:|.::|::.:|...
Frog   945 AE-----NVSCDCDHLTSFSILM--SYKA-----------VDSIVLDYITYIGLAISIISLLICI 991

  Fly   521 LTAALFKSWRS--QASTKVLLHLCLAMCLQMMLF------------VFLNTDDVSEALVVNGNTV 571
            ....|.  |:|  :..|..:.|:||......:|.            ..|.:|.::.|     |:.
Frog   992 TIEGLI--WKSVTKNKTSYMRHVCLVNIAVSLLIADIWFIIGSAISTLLKSDPLNTA-----NSN 1049

  Fly   572 RCVALGAAMQYSILVLFSWMLIIAFLQFQRYVTVIGIERPPRYILKAAIVAWLLPLVPTLLVALI 636
            .||:......:..|.||.|||.:..:.|.|.|.|:......|.:..|..:.:..||:.:::...:
Frog  1050 ACVSATFFTHFFYLSLFFWMLTMGLILFYRLVYVLHDMSKSRMMAIAFTMGYGCPLLISIITVAV 1114

  Fly   637 DPDSYVPSAAQLSTDTGICYPSGYG---------LIFGVVLPVTLITVCNLVIFVYVFYSISHSL 692
                         |..|..|.:|..         .....|||...|.:.|.:|...|...:....
Frog  1115 -------------TQPGRTYLNGNACWLNFSDSKAFIAFVLPALTIILVNFIILAVVIIKLLRPS 1166

  Fly   693 SQSIHKNEKKMVVKQIRLSI-MLFFLLGLTWIFGIFAFMQAGVAFSY-LFCITATMQGFVMFIYF 755
            .....|.|.|..:..|..|| :|..||||||.|||...:.....:.. :|....::||..:.::.
Frog  1167 VGDKPKKEDKSTLIHIGKSIAILTPLLGLTWGFGIATIIAPDALWVLGIFAALNSLQGLFILLFG 1231

  Fly   756 VLLDSTNR 763
            .|||...|
Frog  1232 CLLDKKVR 1239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11318	NP_651842.3	GPS	437..475	CDD:280071	11/39 (28%)
CG11318	NP_651842.3	7tm_4	500..750	CDD:304433	65/274 (24%)
adgrf1	NP_001107298.1	SEA	169..>232	CDD:279699
		IG_like	277..359	CDD:214653
		ig	277..357	CDD:278476
		GAIN	723..>806	CDD:293098	16/109 (15%)
		GPS	924..961	CDD:280071	12/41 (29%)
		7tm_4	1010..1227	CDD:304433	54/234 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000