Protein Alignment CG15553 and SLC46A2

DIOPT Version :9

• Sequence 1: NP_651841.3
• Gene: CG15553 / 43677
• FlyBaseID: FBgn0039817
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 97/454 - (21%)
• Similarity: 175/454 - (38%)
• Gaps: 82/454 - (18%)

  Fly    75 AIETELQDYVANMFLTRTLFESIMPAICGLFVGSWSDQYGRKPLMIVSLVGFSAS---ALISSII 136
            |:|.:.|..::|.::...|...:.|.:....:|..||:|.||..:.:||:||..|   .|:..::
Human    65 ALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLL 129

  Fly   137 CW-LSSYYMVNPWWYTLAAVPHSVLGGWCVFSVAAFCFITDTTDMKTRPYRMIFMEIILFVALTS 200
            .| :...|.        ||..:.:.||:..|........:..:....|..|:|.::::|.:|...
Human   130 DWPVEVLYG--------AAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFC 186

  Fly   201 GSLLSSFVYAATSSAFVQ-------SLSCLIVIIATLFIIFYLPESLGMSPEEDEIPEKEKNVVV 258
            ||:.|..::...:....|       |:||....:....::..:|||:..       |.:|...|.
Human   187 GSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAK-------PSQELPAVD 244

  Fly   259 TV---------LDHKNKTNEISAEAEKTENCDDPPKYESPEKPLEDKVEKAGLFSIKHVKDMFST 314
            ||         ||......:.:.        ..||   ||.|....|...|.||
Human   245 TVSGTVGTYRTLDPDQLDQQYAV--------GHPP---SPGKAKPHKTTIALLF----------- 287

  Fly   315 CFKKRENNAHTIIWLVTLAGFVSI---FVADGVMTVNYLFVRQQFHFTVRDFTIFETFSQSVPML 376
                    ...||:.:.:.|.|.:   ||....:..|.:   |..:.....:|||.|
Human   288 --------VGAIIYDLAVVGTVDVIPLFVLREPLGWNQV---QVGYGMAAGYTIFIT-------- 333

  Fly   377 GAVLGILILRKFFGLSVVALALLSLLSEVAANIARGFAYLSWHLYLSVVLGIFRSIQGPMFRTIV 441
             :.||:|:..:.|  ....:.::.::|..:..:...|...::..|::..:.:|..|.....|:.:
Human   334 -SFLGVLVFSRCF--RDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIPVTTIRSAM 395

  Fly   442 SNIVPPSDTGKLFAIGNILQSFAPFVAAPLYTAIYKESLASNPGGFNFLSAAFYGLAFILIGWV 505
            |.::..|..||:|.|..:..:....|.:.||..||:.::....|....||:....||.|.|..|
Human   396 SKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIV 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	80/395 (20%)
		MFS	97..239	CDD:304372	33/152 (22%)
SLC46A2	NP_149040.3	MFS_1	84..421	CDD:284993	79/395 (20%)
		MFS	<282..453	CDD:304372	40/203 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154040
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.880