DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15553 and Mfsd14b

DIOPT Version :9

Sequence 1:	NP_651841.3	Gene:	CG15553 / 43677	FlyBaseID:	FBgn0039817	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001100804.1	Gene:	Mfsd14b / 306687	RGDID:	1308377	Length:	507	Species:	Rattus norvegicus

Alignment Length:	512	Identity:	102/512 - (19%)
Similarity:	172/512 - (33%)	Gaps:	144/512 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EKASLSQLKTLEWGRLFNMFYIEPVLFMLIFSHMLSGTVMRNQLIYQACTVIFQYNETDCKLLDS 66
            ||...:|..:..|.:.|....:....|::.|.....|.:....|     ||:   :||
  Rat    26 EKRGSAQAASSSWLQGFGQPSVYHAAFVIFFEFFAWGLLTTPML-----TVL---HET------- 75

  Fly    67 KNTTTEIQAIETELQDYVANMFLTRTLFESIMPAICGL---FVGSWSDQYGRKPLMIVSLVGFSA 128
                            :..:.||...|.:.:...:..|   .:|:.||.:||||.:: ..|.|:
  Rat    76 ----------------FPQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLL-GTVFFT- 122

  Fly   129 SALISSIICWLSSYYMVNPWWYTLAAVPHSVLGGWCVFSV---AAFCFITDTTDMKTRPYRMIFM 190
                    |:......::|||| ...:  ||.|   ||||   ..|.::.|.|....|.....::
  Rat   123 --------CFPIPLMRISPWWY-FGMI--SVSG---VFSVTFSVIFAYVADFTQEHERSTAYGWV 173

  Fly   191 EIILFVALTSGSLLSSFVYAATSSAFVQSLSCLIVIIATLFIIFYLPESLGMSPEEDEIPEKEKN 255
            ......:|.|...:.:::.:....:.|..::.::.::...||:..:||||         ||
  Rat   174 SATFAASLVSSPAIGTYLSSNYGDSLVVLVATVVALLDICFILVAVPESL---------PE---- 225

  Fly   256 VVVTVLDHKNKTNEISAEAEKTENCDDPPKYESPEKPLEDKVEKAGLFSIKHV-KDMFSTCFKKR 319
                      |....|..|:.:....||                  ..|:|.| ||
  Rat   226 ----------KIRPASWGAQISWKQADP------------------FASLKKVGKD--------- 253

  Fly   320 ENNAHTIIWLVTLAGFVSIFVADGVMTVNYLFVRQQFHFTVRDFTIFETFSQSVPMLGAVLGILI 384
                 :.:.|:.:..|:|.....|..:..:|::||...|.......|      :.|:| :|.||.
  Rat   254 -----STVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIVAF------IAMVG-ILSILA 306

  Fly   385 LRKFFGLSVVAL-----ALLSLLSEVAANIARGFAYLSWHLYLSVVLGIFRSIQGPMFRTIVSNI 444
            ...|....:.:|     .||.|..::......||...:|.::.:..:....||..|....::|..
  Rat   307 QTVFLSKLMRSLGNKNTVLLGLGFQILQLAWYGFGAQAWMMWAAGTVAAMSSITFPAVSALISRN 371

  Fly   445 VPPSDTGKLFAIGNILQSFAPFVAAPLYTAIYKESLASNPGGFNFLSAAFYGLAFIL 501
            ......|               ||..:.|.|        .|..|.|..|.||..|.|
  Rat   372 AESDQQG---------------VAQGIITGI--------RGLCNGLGPALYGFIFYL 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	75/384 (20%)
CG15553	NP_651841.3	MFS	97..239	CDD:304372	32/147 (22%)
Mfsd14b	NP_001100804.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		MFS_MFSD14	47..452	CDD:340945	97/491 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	462..483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D763423at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820