DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15553 and SPAC14C4.07

DIOPT Version :9

Sequence 1:	NP_651841.3	Gene:	CG15553 / 43677	FlyBaseID:	FBgn0039817	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_594912.1	Gene:	SPAC14C4.07 / 2541546	PomBaseID:	SPAC14C4.07	Length:	644	Species:	Schizosaccharomyces pombe

Alignment Length:	597	Identity:	125/597 - (20%)
Similarity:	217/597 - (36%)	Gaps:	188/597 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LSQLKTLEWGRLFNMFYIEPVLFMLIFSHMLSGTVMRNQLIYQACTVIFQYNETD-------CKL 63
            |:.:....||    |..| |:||:|           |.:|    |.:.:..:.|.       |:|
pombe   134 LNFINAFSWG----MIEI-PLLFLL-----------RQEL----CAIHYNLDPTQLSPDDPICRL 178

  Fly    64 LDSKNTTTEIQAIETELQDYVANMFLTRTLFESIMPAICGLF----VGSWSDQYGRKPLMIVSLV 124
            .:   .||.:..:              |..|.| :.|..|||    .|:..|.|||:.::.:: |
pombe   179 AE---ITTGVSKV--------------RAAFGS-LAAFLGLFSTAYYGTMGDIYGRRLVLFIT-V 224

  Fly   125 GFSASALISSIICWL--SSYYMVNPWWYTLAAVPHSVLGGWCVFSVAA-FCFITDTTDMKTRPYR 186
            .|   .|:..:  ||  .||...:|::...||.... |||:....||: ..|:.|.:..:.|.:.
pombe   225 SF---LLLGDL--WLLYQSYAPKHPYFVLFAAALKG-LGGYISTVVASQNSFVADCSKTEFRAWY 283

  Fly   187 MIFMEIILFVALTSGSLLSSFVYAATSSA-FVQSLSCLIVIIATLFIIFYLPESLGMSPEEDEIP 250
            :........:....|..||.|:...|... :|..::....||..|::...|||||.:|
pombe   284 LGLNFAAYHLGTALGPSLSGFIVQYTPHMYYVFYITSTFWIIYLLYVWLILPESLDVS------- 341

  Fly   251 EKEKNVVVTVLDHKNKTNEISAEAEKTENCDDP-----PKYESPEKPLEDKVEKAGLFSIKHVKD 310
                       :.|.:.|:||..:....:|.:|     |:....|:..|
pombe   342 -----------ESKEQQNKISGFSSIWRSCLEPLIILWPRSLCTEESCE---------------- 379

  Fly   311 MFSTCFKKRENNAHTII----WLVTLAG-FVSI-FVADGVMTVNYLFVRQQFHFTVRDFTIF--- 366
                 |.:.:.||.|..    |.|.||. .:|: .:..|.|.:..|:...:|.:.....::.
pombe   380 -----FHQYDINADTHAGRRHWDVLLAAILISLTLLGAGSMGLLPLYTDYKFGWGPMKASLILST 439

  Fly   367 ETFSQSV------PMLGAVLGILI------------------------LRKFFGLSV-------- 393
            ::|:.|:      |:|..|:..:|                        :|..|...|
pombe   440 DSFASSITLVALFPLLSKVIEKIIEKLYSSEGLFEDPSRADNTSSLQGIRNVFSYLVRPGYSRSS 504

  Fly   394 --------------------------VALALLSLLSEVAANIARGFAYLSWHLYLSVVLGIFRSI 432
                                      :||:...||:...:::|         |:.:|::....::
pombe   505 ILRGRTADEKYTIVKRDVWNAQLGYAIALSAAVLLAVAKSDVA---------LFTAVIIQAISNM 560

  Fly   433 QGPMFRTIVSNIVPPSDTGKLFAIGNILQSFAPFVAAPLYTAIYKESL-ASNPGGFNFLSAAFYG 496
            ..|..::|..|.|.....|::.|...:.::.|..:..|:|..:|.||: .|.|....||||..||
pombe   561 VVPCVQSIALNGVQSEYNGRVLAAFAVFEAVALIIRGPIYAFVYTESMKVSYPNMIFFLSAVIYG 625

  Fly   497 LAFILIGWVMRI 508
            ..||:| :.||:
pombe   626 CCFIII-FFMRL 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	88/458 (19%)
CG15553	NP_651841.3	MFS	97..239	CDD:304372	38/149 (26%)
SPAC14C4.07	NP_594912.1	MFS	190..>335	CDD:119392	38/152 (25%)
SPAC14C4.07	NP_594912.1	MFS_1	194..459	CDD:284993	69/311 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.940