DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15553 and CG30344

DIOPT Version :9

Sequence 1:	NP_651841.3	Gene:	CG15553 / 43677	FlyBaseID:	FBgn0039817	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	160/493 - (32%)
Similarity:	276/493 - (55%)	Gaps:	49/493 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FNMFYIEPVLFMLIFSHMLSGTVMRNQLIYQACTVIFQYNETDCK-LLDSKNTTTEIQAIETELQ 81
            :..|.:||.:|::.|:..|.|.|.:||::||.|..|.::|.|.|: ||.....:...:.:|..:|
  Fly    49 YRWFILEPAVFLIFFARNLIGAVYQNQILYQTCITIEKFNATQCEPLLGIDRGSDADKEVEVIVQ 113

  Fly    82 DYVANMFLTRTLFESIMPAICGLFVGSWSDQYGRKPLMIVSLVGFSASALISSIICWLSSYYMVN 146
            .|.||:.:|.:|.|||:||...||:|.|||::||:|:::.:..|:...|||..:|.:::....::
  Fly   114 TYSANIMMTTSLLESIIPAFASLFLGPWSDKFGRRPILLTTFTGYLTGALILIVITYITRSTNIS 178

  Fly   147 PWWYTLAAVPHSVLGGWCVFSVAAFCFITDTTDMKTRPYRMIFMEIILFVALTSGSLLSSFVYAA 211
            |||:.|::||..|.||.|......:|:|:|....:.:..||:..|..|...:..|::.|.::|||
  Fly   179 PWWFLLSSVPSVVSGGTCALITGIYCYISDVAKERKKALRMVLNEASLCAGIMVGNVASGYIYAA 243

  Fly   212 TSSAFVQSLSCLIVIIATLFIIFYLPESLGMSPEEDEIPEKEKNVVVTVLDHKNKTNEISAEAEK 276
            |::..:.|::..:::.|.::::.::||||
  Fly   244 TNALVLFSIAGSLMMFALMYVLLFVPESL------------------------------------ 272

  Fly   277 TENCDDPPKYESPEKPLEDKVEKAGLFSIKHVKDMFSTCFKKRENNAHTIIWLVTLAGFVSIFVA 341
                 :|....:..:..|       .|....|.|:..||||:|.|...|||||..:|..::||..
  Fly   273 -----NPGDIHTGSRVRE-------FFRFDLVTDLIRTCFKRRPNFDRTIIWLTMIALTIAIFDM 325

  Fly   342 DGVMTVNYLFVRQQFHFTVRDFTIFETFSQSVPMLGAVLGILILRKFFGLSVVALALLSLLSEVA 406
            :|..||||:||:.:|::|::||::|......:.::|:::|:|:||:...:|:|.:|:|||...|.
  Fly   326 EGESTVNYMFVQDKFNWTIKDFSLFNASRIVIQIVGSIVGMLVLRRVLKMSIVTMAMLSLACCVL 390

  Fly   407 ANIARGFAYLSWHLYLSVVLGIFRSIQGPMFRTIVSNIVPPSDTGKLFAIGNILQSFAPFVAAPL 471
            .:..|..|.....|||.:.||:.|.:.|||.|.|:|::.|.::.||:||:...::|.:|..||||
  Fly   391 ESTVRATAVYWQELYLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFALTTSMESVSPLGAAPL 455

  Fly   472 YTAIYKESLASNPGGFNFLSAAFYGLAFILIGWVMRIK 509
            ||.:||.:|.:.||.|||:|||.|.:.:|||..:..|:
  Fly   456 YTTVYKATLENYPGAFNFISAALYFVCYILIAVIFGIQ 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	111/372 (30%)
CG15553	NP_651841.3	MFS	97..239	CDD:304372	43/141 (30%)
CG30344	NP_724759.1	MFS	113..490	CDD:119392	139/424 (33%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	110/367 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458929
Domainoid	1	1.000	92	1.000	Domainoid score	I7560
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4421
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		mtm6480
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
	10	9.900