DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15553 and slcr-46.3

DIOPT Version :9

Sequence 1:	NP_651841.3	Gene:	CG15553 / 43677	FlyBaseID:	FBgn0039817	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_505506.2	Gene:	slcr-46.3 / 185544	WormBaseID:	WBGene00009582	Length:	585	Species:	Caenorhabditis elegans

Alignment Length:	522	Identity:	120/522 - (22%)
Similarity:	219/522 - (41%)	Gaps:	72/522 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 IEPVLFMLIFSHMLSGTVMRNQLIYQACTVIFQYNETDCKLLDSKN-TTTEIQAIETELQDYVAN 86
            :||:||:::...   |.:..|..::.......|..:|..:|.|:.. |...|.:....|||.|..
Worm    62 VEPILFLVMCGF---GLMTTNNSLFTYWARCVQIAQTHRELADNATYTCASIASSNGTLQDDVEK 123

  Fly    87 MFLTRTLFESIMPAICGLFV----GSWSDQYGRKPLMIVSLVGFSASALISSIICWLSSYYMVNP 147
            ......::..||..|..|.|    |:|||:.|||..::.||.|...:..|  ::|...:|..||.
Worm   124 DIANTKIYLQIMGTIPTLIVSPLIGNWSDRNGRKSPLLFSLFGLFINNFI--LLCATLTYETVNV 186

  Fly   148 -WWYTLAAVPHSVLGGWCVFSVAAFCFITDTTDMK------TRPYRMIFMEIILFVALTSGSLLS 205
             :|:.::.....:.||.......:...:||....|      |.|:|:.....:..:.:.:|:|:.
Worm   187 YYWFFISEFMLGMFGGGAATFSTSLAIVTDDCRHKLKPGSSTVPFRVGLASFVQSIGMLNGTLIV 251

  Fly   206 SFV------------YAATSSAFVQSLSCLIVIIATLFIIFYLPESLGMSPEEDEIPEKEKNVVV 258
            |.:            .:....||:|:...||.:|..:|.:           .|...|:||
Worm   252 SLLAVPAIISVERHALSYVECAFIQTALSLISLIYAIFFV-----------RETHFPKKE----- 300

  Fly   259 TVLDHK-NKTNEISAEAEKTENCDDPPKYESPEKPLEDKVEKAGLFSIKHVKDMFSTCFKKRENN 322
               |.. |:.|    |||:.|..:.|||.....:           |: .:::::|.....:|.
Worm   301 ---DFSYNQLN----EAEEVEAEELPPKIIGMRR-----------FT-SYLENVFGVLTVRRP-- 344

  Fly   323 AHTIIWLVTLAGFVSI-FVADGVMTVNYLFVRQQFHFTVRDFTIFETFSQSVPMLGAVLGILILR 386
            ..|.:.|.....||.| |::.....:..|..|..|.:..:.|:.|....|.|...|.:|..::|.
Worm   345 GWTRLCLCVSLAFVFIEFLSFDPALLLLLVKRLPFAWNDKLFSYFSLTRQLVNCFGMILCPILLT 409

  Fly   387 KFFGLSVVALALLSLLS-EVAANIARGFAYLSWHLYLSVVLGIFRSIQGPMFRTIVSNIVPPSDT 450
            ....|...:|.:::.|: ..|.:....||..:.|::.:.:.||......|.:|:.:..:|...:|
Worm   410 FSHWLGKDSLLIIAALACSAATSFLTAFATRTEHIFYTCIFGIVMGGMQPAYRSFLPRMVAKEET 474

  Fly   451 GKLFAIGNILQSFAPFVAAPLYTAIYKESLASNPGGFNFLSAAFYGLAFI---LIGWVMRIKFKH 512
            .:|..:.:|:.||:|.:::.::..|:..:|...||...|:|..|....||   :|..:||.::|.
Worm   475 ARLLTVVSIIISFSPILSSLIFNNIFNMTLTWWPGFAFFVSGCFQITVFIGQLVIHMLMRPQWKL 539

  Fly   513 QK 514
            .|
Worm   540 DK 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	90/398 (23%)
CG15553	NP_651841.3	MFS	97..239	CDD:304372	39/164 (24%)
slcr-46.3	NP_505506.2	MFS_SLC46	59..530	CDD:340944	115/509 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163338
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3339
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		otm14610
orthoMCL	1	0.900	-	-		OOG6_153665
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.790