DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15553 and Mfsd14a

DIOPT Version :9

Sequence 1:	NP_651841.3	Gene:	CG15553 / 43677	FlyBaseID:	FBgn0039817	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_032272.2	Gene:	Mfsd14a / 15247	MGIID:	1201609	Length:	490	Species:	Mus musculus

Alignment Length:	460	Identity:	96/460 - (20%)
Similarity:	160/460 - (34%)	Gaps:	151/460 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 QDYVANMFLTRTLFESIMPAICGL---FVGSWSDQYGRKPLMIVSLVGFSASALISSIICWLSSY 142
            :.:..:.||...|.:.:...:..|   .:|:.||.:|||..:::: |.|:.:.:         ..
Mouse    64 ETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLT-VFFTCAPI---------PL 118

  Fly   143 YMVNPWWYTLAAVPHSVLGGWCVFSVAAFCFITDTTDMKTRPYRMIFMEIILFVALTSGSLLSSF 207
            ..::|||| .|.:  ||.|.:.|.....|.::.|.|....|.         :...|.|.:..:|.
Mouse   119 MKISPWWY-FAVI--SVSGVFAVTFSVVFAYVADITQEHERS---------MAYGLVSATFAASL 171

  Fly   208 VYAATSSAFVQSL--SCLIVIIAT-------LFIIFYLPESLGMSPEEDEIPEKEKNVVVTVLDH 263
            |.:....|::..:  ..|:|::||       .||:..:||||         |||.:
Mouse   172 VTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESL---------PEKMR--------- 218

  Fly   264 KNKTNEISAEAEKTENCDDPPKYESPEKPLEDKVEKAGLF-SIKHVKDMFSTCFKKRENNAHTII 327
                               |..:.:|     ...|:|..| |:|.|             ...:|:
Mouse   219 -------------------PASWGAP-----ISWEQADPFASLKKV-------------GQDSIV 246

  Fly   328 WLVTLAGFVSIFVADGVMTVNYLFVRQQFHFTVRDFTIFETFSQSVPMLGAVLGILILRKFFGLS 392
            .|:.:..|:|.....|..:..:|::||...|:          .:||....|||||        ||
Mouse   247 LLICITVFLSYLPEAGQYSSFFLYLRQIMKFS----------PESVAAFIAVLGI--------LS 293

  Fly   393 VVALAL-LSLLSEVAAN-----IARGFAYLS----------WHLYLSVVLGIFRSIQGPMFRTIV 441
            ::|..: ||||.....|     :..||..|.          |.::.:..:....||..|....:|
Mouse   294 IIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALV 358

  Fly   442 SNIVPPSDTGKLFAIGNILQSFAPFVAAPLYTAIYKESLASNPGGFNFLSAAFYGLAFILIGWVM 506
            |........|               |...:.|.|        .|..|.|..|.||..|    ::.
Mouse   359 SRTADADQQG---------------VVQGMITGI--------RGLCNGLGPALYGFIF----YIF 396

  Fly   507 RIKFK 511
            .::.|
Mouse   397 HVELK 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	83/401 (21%)
CG15553	NP_651841.3	MFS	97..239	CDD:304372	34/153 (22%)
Mfsd14a	NP_032272.2	MFS_MFSD14	37..449	CDD:340945	96/460 (21%)
Mfsd14a	NP_032272.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	466..490
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810