DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15553 and LOC100487354

DIOPT Version :9

Sequence 1:	NP_651841.3	Gene:	CG15553 / 43677	FlyBaseID:	FBgn0039817	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	XP_017953038.2	Gene:	LOC100487354 / 100487354	-ID:	-	Length:	462	Species:	Xenopus tropicalis

Alignment Length:	526	Identity:	102/526 - (19%)
Similarity:	192/526 - (36%)	Gaps:	155/526 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YIEPVL--FMLIFSHMLSGTVMRNQLIYQACTVIFQYNETDCKLLDSKNTTTEIQAIETELQDYV 84
            :||||:  ..:..|...:|.:|         ||...||:|    :.|.|::.     :.:||..:
Frog     5 WIEPVVAGAQIASSFYDTGLLM---------TVENYYNQT----IISSNSSR-----DDDLQKAI 51

  Fly    85 ANMFLTRTLFESIMPAICGLFVGSWSDQYGRKPLMIVSLVGF--------------------SAS 129
            :|.::...:...:.|.:....:...||:...|..:.|.|.|:                    ..|
Frog    52 SNFYIIYNVVMGMTPLLSAYILAKISDKTSTKVTICVPLTGYLISRMFLLFVILFEWPIEVIFGS 116

  Fly   130 ALISSIICWLSSYYMVNPWWYTLAAVPHSVLGGWCVFSVAAFCFITDTTDMKTRPYRMIFMEIIL 194
            |..:.:..|.::|:.....|.:||                       :|:.| |..::|.:|::.
Frog   117 AAFNGLTGWFTTYWAGVMAWASLA-----------------------STESK-RSLKLIIIELVY 157

  Fly   195 FVALTSGSLLSSFVYAATS-----SAFVQSLSCLIVIIATLFIIFYLPESLGMSPEEDEIPEKEK 254
            .:|..:|||:|.:::...:     ...:.|.|........|:.||.|           ::|:.|
Frog   158 GLAGFAGSLVSGYIFVHLNINKHQGTILASCSTGCYAFCVLYSIFIL-----------KMPDAE- 210

  Fly   255 NVVVTVLDHKN----KTNEISAEAEKTENC---DDPPKYESPEKPLEDKVEKAGLFSIKHVKDMF 312
                |.|:.:|    ..||.|.|:..:: |   :|.|...:...|.:....|..:..      ||
Frog   211 ----TCLEERNTEGSSINEASQESINSD-CALLNDKPTNNTAINPSDVASSKCVIIC------MF 264

  Fly   313 STCFKKRENNAHTIIWLVTLAG---FVSIFVAD-----GVMTVNYLFVRQQFHFTVRDFTIFETF 369
                      ...|::.:.:..   .:::||..     |.:.|.|           .:...:.|:
Frog   265 ----------VSAIVYNIAVTATDDVINVFVLKKPLNWGPVEVGY-----------GNAAAYMTY 308

  Fly   370 SQSVPMLGAVLGILILRKFFGLSVVALALLSLLSEVAANIARGFAYLSWHLYLSVVLGIFRSIQG 434
                  :.:.||:.|..|.||  .:.|.:..::|.....:...|...::..|::..:.:|..|..
Frog   309 ------ITSFLGVYIFSKCFG--DLGLIITGMISFSCGILIMAFVRWTYLYYIARAVMLFSLITT 365

  Fly   435 PMFRTIVSNIVPPSDTGKLFAIGNILQSFAPFVAAPLYTAIYKESLASNPGGFNFLSAA----FY 495
            |..|:|:|..|..|..|::|.   :||.....:|            .|:..|||.|..|    |.
Frog   366 PTIRSIISKHVKGSSYGQVFV---VLQMAIEVIA------------VSSSAGFNKLYQATLDWFS 415

  Fly   496 GLAFIL 501
            |..|::
Frog   416 GFCFLV 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	75/412 (18%)
CG15553	NP_651841.3	MFS	97..239	CDD:304372	30/166 (18%)
LOC100487354	XP_017953038.2	MFS_SLC46A2_TSCOT	3..437	CDD:341008	102/526 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47543
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020