DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15553 and LOC100002406

DIOPT Version :9

Sequence 1:	NP_651841.3	Gene:	CG15553 / 43677	FlyBaseID:	FBgn0039817	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	XP_017213485.1	Gene:	LOC100002406 / 100002406	-ID:	-	Length:	424	Species:	Danio rerio

Alignment Length:	514	Identity:	102/514 - (19%)
Similarity:	182/514 - (35%)	Gaps:	142/514 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YIEPVLFMLIFSHMLSGTVMRNQLIYQACTVIFQYNETDCKLLDSKNTTTEIQAIETELQDYVAN 86
            ||.|::|....:.....|.:: .::.:.|.     |.||.   |.:             |..:.|
Zfish     7 YIAPLVFSAQVASSFFDTALQ-MVVKERCA-----NATDS---DGQ-------------QKAITN 49

  Fly    87 MFLTRTLFESIMPAICGLFVGSWSDQYGRKPLMIVSLVGFSAS---ALISSIICW-LSSYYMVNP 147
            ..:|..:....||.:..:.:....|:..||..::|.|||:..|   .|:.....| |...|
Zfish    50 FNMTYNMIAKFMPFLPAILLAKVGDRGYRKVPIVVPLVGYFLSRGLLLLDVAFDWPLQVLY---- 110

  Fly   148 WWYTLAAVP--HSVLGGWCVFSVAAFCFITDTTDMKTRPYRMIFMEIILFVALTSGSLLSSFVYA 210
                  |||  |.:.||:..:.......::.::..:.|...::..|::..:|...|||.|..::|
Zfish   111 ------AVPVIHGLCGGFASYWAGVMALVSVSSGEEERSVSIMMTELVYGIAGFIGSLASGHLFA 169

  Fly   211 -----------ATSSAFVQSLSCLIVIIATLFIIFYLPESLGMSPEEDEIPEKEKNVVVTVLDHK 264
                       .:.|:.|..|.||  :.|..|:....|..||     |.:..:|.   ..:::|:
Zfish   170 LYTVNLKQGVILSGSSVVLYLLCL--LYAATFLRVGPPAVLG-----DRLERRES---FGIINHE 224

  Fly   265 NKTNEISAEAEKTENCDDPPKYESPEKPLEDKVEKAGLF--------SIKHVKDMFSTCFKKREN 321
            .:                            ||:..|.||        ::....:|.:....|...
Zfish   225 AR----------------------------DKINIALLFVSGILYDIAVAGGMEMLAAYVLKEPL 261

  Fly   322 NAHTIIWLVTLAGFVSIFVADGVMTVNYLFVRQQFHFTVRDFTIFETFSQSVPMLGAVLGILILR 386
            |     |..||.|:       |....:.||:..  ...|:.||......:|:.|:|.|
Zfish   262 N-----WGATLVGY-------GNAAGSLLFITS--FLGVKMFTRLSLRDESMIMVGMV------- 305

  Fly   387 KFFGLSVVALALLSLLSEVAANIARGFAYLSW-----HLYLSVVLGIFRSIQGPMFRTIVSNIVP 446
                                 :.|.|..::::     ..:|:..:.:|..|..|..|:::|..|.
Zfish   306 ---------------------SFATGIYFMAFVTTTPMYFLARSVTLFALIPMPTIRSLLSKQVK 349

  Fly   447 PSDTGKLFAIGNILQSFAPFVAAPLYTAIYKESLASNPGGFNFLSAAFYGLAFILIGWV 505
            .:..|..|.:..:....|.....|:||.||:.:|.:.||....||:.|..|:.:.|..|
Zfish   350 GTSYGITFVMLQLSFKLASLATTPIYTKIYQATLDTFPGFVFILSSIFTVLSIVPISIV 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	75/402 (19%)
CG15553	NP_651841.3	MFS	97..239	CDD:304372	36/158 (23%)
LOC100002406	XP_017213485.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6513
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950