Protein Alignment nkx6.1 and HGTX

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 145/327 - (44%)
• Similarity: 178/327 - (54%)
• Gaps: 96/327 - (29%)

Zfish     7 MDGSRQSAFLLNTPPLAALHSM-TEMKTP------------LYPAYPLS-------STGPASSTS 51
            ||.....:||  .||||||||| ||||..            .|...|.|       |.|.:||:|
  Fly   284 MDHKLPLSFL--GPPLAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLISDRGSGGSSSSSS 346

Zfish    52 PTATSPNPGGIPVSSPGIKTSSGLSALASAQQCAIATPHGINDILSRPSVACSPAGIL----SGL 112
            .|.|:.|..|.|                        .||||:.|||:|....| ||:.    :|:
  Fly   347 TTTTNTNSQGAP------------------------NPHGIDTILSKPPPVTS-AGLSALTGAGI 386

Zfish   113 PRFSSLSPPPPPGLYFSPSAAAVAVARY-----PKPLTELPG----RTPIFWP---GVMQSP-HW 164
            ||||.             :|||..:|:|     ..||....|    ||.::||   |::.:| .|
  Fly   387 PRFSI-------------AAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAW 438

Zfish   165 RD-------ARFACSPHQNSVLLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYS 222
            |:       |..:.| ||:....|||||:|||||||||||||||||||||||||||||||:|||:
  Fly   439 RERLSNTMSANLSQS-HQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYA 502

Zfish   223 LGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSETERLKGASENEDDDDDYNKPLDPNSDDE 287
            |||:||||||||||||||||||||||||:||:|||.    :.|     |:|.|.::.:|  ||:|
  Fly   503 LGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDD----MGG-----DNDGDCSETMD--SDNE 556

Zfish   288 KI 289
            .:
  Fly   557 SL 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	53/57 (93%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	42/130 (32%)
		Homeodomain	465..523	CDD:459649	53/57 (93%)