Protein Alignment nkx6.1 and Dr

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 305
• Identity: 92/305 - (30%)
• Similarity: 121/305 - (39%)
• Gaps: 103/305 - (33%)

Zfish    18 NTPPLAALHSMTEMKTPLYPAYPLSSTGPASST-------SPTAT-------------------- 55
            |:||  |..|.|...|||..|  |.|.|..:||       ||..:
  Fly   235 NSPP--ASTSSTPSSTPLGSA--LGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADH 295

Zfish    56 -----------SPNPGGIPVSSPGIKTSSGLSALASAQQCAIATPHGINDILSRPSVACSPAGIL 109
                       ..|....|.|:|.....||.|         :.:|||........|...|||.:.
  Fly   296 DEEEDSIVDIEDMNADDSPRSTPDGLDGSGKS---------LESPHGPPPGSHMQSTILSPAALA 351

Zfish   110 SG-LPRFSSLSPPPPPGLYFSPSAAAVAVARYPKPLTELPGRTPIFWPGVMQSPHW--------- 164
            || :|    :.|.|     ||..||| |||     .|.:.|..|  |||..|.|.:
  Fly   352 SGHVP----IRPTP-----FSALAAA-AVA-----WTGMGGGVP--WPGTRQMPPFGPPGMFPGA 399

Zfish   165 ---RDA----RFACSPHQNSVLLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYS 222
               .||    |..|:       |.|....:..|..|:.||:.:|||.|.:.:||:..|||..:.|
  Fly   400 GFGGDANEPPRIKCN-------LRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSS 457

Zfish   223 LGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSETERLKGAS 267
            |.:||:|||:||||||.|           ||:.|::|.|::|.|:
  Fly   458 LRLTETQVKIWFQNRRAK-----------AKRLQEAEIEKIKMAA 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	27/57 (47%)
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	28/66 (42%)