Protein Alignment nkx6.1 and tin

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 72/285 - (25%)
• Similarity: 104/285 - (36%)
• Gaps: 64/285 - (22%)

Zfish    13 SAFLLNTPPLAALHSMTEMKTPLYPAYPLSSTGPA-SSTSPTATSPNPGGIPVSSPGIKTSSGLS 76
            ||:.::.....|..|.|..:||....|..:.:|.. ...:|:|.......||  :|.:..|..|.
  Fly   155 SAYNMSASQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIP--TPYVTPSPTLD 217

Zfish    77 ALASAQQCAIATPHG---INDILSRPSVACSPAGILSGLPRFSSLSPPPPPGLYFSPSAA----- 133
            ..:||:..::..|..   :|.:..|         ::......|||.     .:|.|...|
  Fly   218 LNSSAEVDSLQAPTQKLCVNPLSQR---------LMETASNSSSLR-----SIYGSDEGAKKKDN 268

Zfish   134 -AVAVARYPKPLTELPGRTPIFWPGVMQSPHWRDARFACSPHQNSVLLDKDGKRKHTRPTFSGQQ 197
             .|..:|.......:.|.:                    :|..||.......||| .|..||..|
  Fly   269 SQVTSSRSELRKNSISGNS--------------------NPGSNSGSTKPRMKRK-PRVLFSQAQ 312

Zfish   198 IFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSETE- 261
            :..||..|...|||.|.||..:|..|.::.:|||:||||||.|            .|:.|.:.|
  Fly   313 VLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYK------------SKRGDIDCEG 365

Zfish   262 ---RLKGASENEDDDDDYNKPLDPN 283
               .||..||..|.......|: ||
  Fly   366 IAKHLKLKSEPLDSPTSLPPPI-PN 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	28/57 (49%)
tin	NP_524433.1	Homeodomain	302..358	CDD:459649	27/68 (40%)