Protein Alignment nkx6.1 and HHEX

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 319
• Identity: 85/319 - (26%)
• Similarity: 130/319 - (40%)
• Gaps: 88/319 - (27%)

Zfish     9 GSRQSAFLLNTPPLAALHSMTEMKTPLYPAYPLSSTGPASSTSPTATSPNPGGIPVSSPGIKTSS 73
            ||.||...: |..:|..|::...|..|       :|| :||.:||   |:|.    |:..|   .
  Fly    32 GSSQSPVAV-TAGIATPHALAMPKASL-------ATG-SSSAAPT---PSPS----SATNI---Y 77

Zfish    74 GLSALASAQQCAIATPHGINDILSRPSVACSPAGILSGLPRFSSLSPPPPPGLY----------- 127
            .||..|:|.|.|:.:...        |...:|..:     ||:.:.|.|....|
  Fly    78 DLSREAAAAQYAMKSMDS--------SAVLAPTSL-----RFNPIYPDPASLFYQQVLQLQKNPS 129

Zfish   128 -FSP--SAAAVAVARYPKPLTELPGRTPIF-----WPGVMQSPHWRDARFACS--PHQNSVLLDK 182
             |.|  .|||||.|...:|.......:|..     :|    :|....|...|:  |..:..:.:.
  Fly   130 LFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFP----NPASAAAALYCNAYPAASFYMSNF 190

Zfish   183 DGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAA 247
            ..|||..:..|:.||...||..|..:|||:..||..||..|.:|:.|||.||||||.|||:.:.:
  Fly   191 GVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLS 255

Zfish   248 EMASAKK-------------------------------KQDSETERLKGASENEDDDDD 275
            :.:::.:                               :|..|.:|:..:.::||||:|
  Fly   256 KRSASAQGPIAGAAVGSPSSASSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDDEDDDED 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	29/57 (51%)
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	26/50 (52%)