Protein Alignment nkx6.1 and ems

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 332
• Identity: 91/332 - (27%)
• Similarity: 131/332 - (39%)
• Gaps: 78/332 - (23%)

Zfish    20 PPLAALHSMTEMKTPLYPAYPLSSTGPASSTSPTATSPN----PGGIPVSSPGIKTSSGLSALAS 80
            |.:|.  |:...::|..||.. .:..||....|..|.|.    ....|.|||.:..||..:....
  Fly   171 PQMAV--SLKRERSPAPPAME-QAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQ 232

Zfish    81 AQQ---------CAIATPHGINDILSRPSVACSPAGIL----------------SGLPRFSSLSP 120
            .||         .|:..|.|...:: .|.:  .|||::                .|||...:|.|
  Fly   233 QQQQQPPPNYPKPAMMHPGGAGPMM-MPGM--PPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPP 294

Zfish   121 ----PP--PP--------------------GLYFSPSAAAVAVARYPKPLTE-LPGRTPIFWPGV 158
                ||  ||                    |....|:|||.|.|..|....: :|.      ||:
  Fly   295 YINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPN------PGM 353

Zfish   159 MQSPH----WRDARFA-CSPHQ--NSVLLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPER 216
            .:..:    |..:|.. ..||:  .|.|:....|.|..|..||..|:..||..||..:|:.|.||
  Fly   354 ARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAER 418

Zfish   217 ARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSETERLKGASENEDDDDDYNKPLD 281
            ..||.:|.::|:||||||||||||.::   .:....|..:......:...|.:||||:..:..:|
  Fly   419 KALAQNLNLSETQVKVWFQNRRTKHKR---MQQEDEKGGEGGSQRNMHNGSGDEDDDELIDMEMD 480

Zfish   282 PNSDDEK 288
            ....||:
  Fly   481 ECPSDEE 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	30/57 (53%)
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/55 (53%)