Protein Alignment nkx6.1 and Dbx

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 87/322 - (27%)
• Similarity: 122/322 - (37%)
• Gaps: 86/322 - (26%)

Zfish    14 AFLLN-TPPLAALHSMTEMKTPLYPAYPLSSTGP---ASSTSPTAT----SPNPGGIPVSSPGIK 70
            |||.: .||    |...:.:..:...:|.:|..|   :||:||.:|    ..|.|....:..|..
  Fly   245 AFLTHQLPP----HQHHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDSDNNHGASTANGNGSG 305

Zfish    71 TSSGLSALASAQQCAIATPHGINDILSRPSVACSPAGILS------------------------- 110
            |.:      |.|.   |.||.:.:  |.|....|.:..|:
  Fly   306 TGN------SGQD---ARPHELAN--SNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGH 359

Zfish   111 GLPRFSSLSPPPPPGLYFSPSAAAVAVARYPKPLTELPGRTPIFWPGVMQSPHWRDARFACSPHQ 175
            |.|     :|||||    .|...|       ||   :|.|...|.|..:..||.......|....
  Fly   360 GHP-----TPPPPP----PPPVIA-------KP---MPSRPTPFLPHTLNHPHLHSLLAHCRNPY 405

Zfish   176 NSV------------------LLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYS 222
            .||                  ...|..:....|..||..|...|||.|:|.||::.|:|.:||..
  Fly   406 MSVGAQVFPLPPGQGFPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAER 470

Zfish   223 LGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSETERLKGASENEDDDDDYNKPLDPNS 284
            ||:.:||||:||||||.|||.....|:.::...:| :|...|.....:..|...::||.|.|
  Fly   471 LGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRD-QTLPNKNNPNPDLSDAKCDRPLTPLS 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	29/57 (51%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	29/53 (55%)