Protein Alignment nkx6.1 and Dll

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Alignment Length: 283
• Identity: 79/283 - (27%)
• Similarity: 108/283 - (38%)
• Gaps: 72/283 - (25%)

Zfish    31 MKTPLYPAYPLSSTGPASSTSPTATSPNPG-GIPVSSPGIKTSSGLSALASAQQCAIATPHGIND 94
            |..|..|..|....|     ..||.|..|| .||          |.||....||.|.|...||..
  Fly     1 MDAPDAPHTPKYMDG-----GNTAASVTPGINIP----------GKSAFVELQQHAAAGYGGIRS 50

Zfish    95 ILSR--PSVACSPAGILSGLPR-FSSLSPPPPPGLYFSPSAAAVAVARYPKPLTELPGRTPIFWP 156
            ....  |.     .|..||.|. .|:|..|.||  ....|.:...:..|..|..
  Fly    51 TYQHFGPQ-----GGQDSGFPSPRSALGYPFPP--MHQNSYSGYHLGSYAPPCA----------- 97

Zfish   157 GVMQSPHWRDARFACSPHQNSVLLDKDGKR-KHTRPTFSGQQIFALEKTFEQTKYLAGPERARLA 220
                ||...|...:.....:.:.::..||: :..|..:|..|:..|.:.|::|:|||.||||.||
  Fly    98 ----SPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELA 158

Zfish   221 YSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSETERLKGASENEDDDDDYNKPLDPNSD 285
            .|||:|::|||:||||||:|::|.    |.:|:....:....|.|...|..
  Fly   159 ASLGLTQTQVKIWFQNRRSKYKKM----MKAAQGPGTNSGMPLGGGGPNPG-------------- 205

Zfish   286 DEKITQLLKKHKPNSALIIHTSE 308
                     :|.||.   :|:.|
  Fly   206 ---------QHSPNQ---MHSGE 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	30/58 (52%)
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	29/55 (53%)