Protein Alignment nkx6.1 and B-H1

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 76/367 - (20%)
• Similarity: 115/367 - (31%)
• Gaps: 148/367 - (40%)

Zfish    20 PPLAA--LHSMTEMKTPLYPAYPLSSTGPASSTSPTATSPNPGGIPVSSPGIKTSSGLSALASAQ 82
            ||..|  :||.|.|           |:|.:::|:.....||.....::.  |...|..:|....|
  Fly    44 PPAVAHSIHSTTTM-----------SSGGSTTTASGIGKPNRSRFMIND--ILAGSAAAAFYKQQ 95

Zfish    83 QCAIATPHGINDILSRPSVACSPA---------------------GILSGLPRFSSLSPPPPPGL 126
            |......|..|:..|..|...|||                     |:|..........||..|..
  Fly    96 QHHQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHT 160

Zfish   127 -------------YFSPSAA--AVAVARYPKPLTELPGRTPIFWPGVMQSPHWRDARFACSPHQN 176
                         :|.|:|.  .:.||:|...:.:                |:..|..|.:...|
  Fly   161 HPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQ----------------HYAAAAAAAAARNN 209

Zfish   177 SVLL------------------------------------------------------------- 180
            :...
  Fly   210 AAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSN 274

Zfish   181 ---DKDG----------------KRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMT 226
               |.||                |::..|..|:..|:..|||:||:.|||:..||..||:.|.::
  Fly   275 GGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLS 339

Zfish   227 ESQVKVWFQNRRTKWRKRHAAEM-ASAKKKQDSETERLKGAS 267
            :.|||.|:|||||||:::.|..: ..|:....:..:||.|.|
  Fly   340 DCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGS 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	28/57 (49%)
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	27/55 (49%)