Protein Alignment nkx6.1 and ind

DIOPT Version :10

• Sequence 1: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Sequence 2: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 70/282 - (24%)
• Similarity: 98/282 - (34%)
• Gaps: 84/282 - (29%)

Zfish    19 TPPLAALHSMTEM--KTPLYPAYPLSSTG-------------------------PASSTSPTATS 56
            :|..||..:...|  ..|:.| ||.|..|                         .|::.:..|..
  Fly    30 SPTAAAAVAAAAMLPSIPMLP-YPASYVGSYLFSLGIQQQQQQQQQQQQHAAAAAAAAAAAAALQ 93

Zfish    57 PNPGGIPVSSPGI------------KTSSGLSALASAQQCAIATPHGINDILSRPSVACSPAGIL 109
            .:|.  ..||||.            :.|||.|   :.:.|..:.|...|.    .|....|...|
  Fly    94 QHPH--VSSSPGSLYHPYAQLFASKRKSSGFS---NYEGCYPSPPLSANP----NSQQLPPIHNL 149

Zfish   110 SGLPRFSSLSPPPPPGLYFSPSAAAVAVARYPKPLTELPGRTPIFWPGVMQSPHWRDARF----A 170
            .|.|....|..|.|.....||||::.|...|.....|..|:                 ||    :
  Fly   150 YGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQGK-----------------RFKHESS 197

Zfish   171 CSPHQN--------------SVLLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAY 221
            |||:.:              .::.|.....|..|..|:..|:..||:.|....||:...|..:|.
  Fly   198 CSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIAN 262

Zfish   222 SLGMTESQVKVWFQNRRTKWRK 243
            .|.::|.|||:||||||.|.:|
  Fly   263 RLRLSEKQVKIWFQNRRVKQKK 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	23/57 (40%)
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	23/55 (42%)