Protein Alignment dco and Csnk1a1

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: XP_006526446.1
• Gene: Csnk1a1 / 93687
• MGIID: 1934950
• Length: 374
• Species: Mus musculus
• Alignment Length: 366
• Identity: 219/366 - (59%)
• Similarity: 260/366 - (71%)
• Gaps: 57/366 - (15%)

  Fly     2 ELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIP 66
            |..||.||:|.|||||||||||||...|..|||||:|||..:.:||||..|||.||.:|||:|||
Mouse    10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIP 74

  Fly    67 RIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKP 131
            .|.|.|.|.||||:||:|||||||||||||||||::||||:|||||||||:|:|:::||||||||
Mouse    75 HIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKP 139

  Fly   132 DNFLMGLGK---------------------------KG-NLVYIIDFGLAKKFRDARSLKHIPYR 168
            ||||||:|:                           .| |.:::||||||||:||.|:.:|||||
Mouse   140 DNFLMGIGRHCNKCLESPVGKRKRSMTVSPSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHIPYR 204

  Fly   169 ENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKL 233
            |:|||||||||||||.|||||||||||:|||||||||||..:|||||||||.|:||||:|||||:
Mouse   205 EDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKM 269

  Fly   234 STSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGP 298
            ||.:.|||||||:||..|||:||.:.|::.|||.:||:|||.||..|...|||.|||.:||
Mouse   270 STPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLK---- 330

  Fly   299 RNPQAIQQAQDGADGQAGHDAVAAAAAVAAAAAASSHQQQQ 339
              .:|.||                       ||:||.|.||
Mouse   331 --QKAAQQ-----------------------AASSSGQGQQ 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	198/301 (66%)
Csnk1a1	XP_006526446.1	STKc_CK1_alpha	16..309	CDD:271030	192/292 (66%)