Protein Alignment dco and HRR25

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_015120.1
• Gene: HRR25 / 855897
• SGDID: S000006125
• Length: 494
• Species: Saccharomyces cerevisiae
• Alignment Length: 328
• Identity: 198/328 - (60%)
• Similarity: 256/328 - (78%)
• Gaps: 10/328 - (3%)

  Fly     1 MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGI 65
            |:||||.|:|:|||||||||||||.||.:.:|||||||||.||::||||..||:.|:.:.||:||
Yeast     1 MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGI 65

  Fly    66 PRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIK 130
            |.|.|.|.||:||.||::|||||||||||:|.||||.|||::||.||..||.|||.|.|||||||
Yeast    66 PFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIK 130

  Fly   131 PDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195
            |||||||:|::|:.|::|||||:||:||..:.:||||||||:|||||||||:|||||||||||||
Yeast   131 PDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDD 195

  Fly   196 LESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHF 260
            ||||||||:||..|:||||||||..|:|||:||.||||:.|:..||.|.|.||..|:.:|:.:.|
Yeast   196 LESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKF 260

  Fly   261 DQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQ-----DGADGQAGHDAV 320
            |::|||..|.:||::|..:|.:..|::|||.:|::     .:|:.:.|     :..|..|..:|.
Yeast   261 DEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRY-----TKAMVEKQRDLLIEKGDLNANSNAA 320

  Fly   321 AAA 323
            :|:
Yeast   321 SAS 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	182/273 (67%)
HRR25	NP_015120.1	Protein Kinases, catalytic domain	8..282	CDD:473864	182/273 (67%)