DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dco and ckl7

DIOPT Version :9

Sequence 1:	NP_001263132.1	Gene:	dco / 43673	FlyBaseID:	FBgn0002413	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001330873.1	Gene:	ckl7 / 834433	AraportID:	AT5G44100	Length:	476	Species:	Arabidopsis thaliana

Alignment Length:	447	Identity:	235/447 - (52%)
Similarity:	303/447 - (67%)	Gaps:	29/447 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGI 65
            |:|.:|.|::||:||||||||::|||..:.||||||:|||.::|||||||.|||.|..:|||.||
plant     1 MDLVIGGKFKLGKKIGSGSFGELYLGVNVQTGEEVAVKLENVKTKHPQLHYESKLYMLLQGGSGI 65

  Fly    66 PRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIK 130
            |.|.|.|.||||:|||::|||||||||||:|:|:.:|||||:||||:::|::::|:|.|:|||||
plant    66 PNIKWFGVEGDYSVMVIDLLGPSLEDLFNYCNRKLTLKTVLMLADQLLNRVEFMHTRGFLHRDIK 130

  Fly   131 PDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195
            |||||||||:|.|.||||||||.||:||.::.|||||||||||||||||||:|||||:|||||||
plant   131 PDNFLMGLGRKANQVYIIDFGLGKKYRDLQTHKHIPYRENKNLTGTARYASVNTHLGVEQSRRDD 195

  Fly   196 LESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHF 260
            |||||||||||..|:||||||||..|:|||:||||||:||.|.||||..|||||:|.::||.:.|
plant   196 LESLGYVLMYFLKGSLPWQGLKAGTKKQKYDRISEKKVSTPIEVLCKNQPSEFVSYFHYCRSLRF 260

  Fly   261 DQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQDGADGQAGHDAVAA--- 322
            |.:|||.:|::|||:||.|.|:.:||||||.:||:     ||.  .:..|:..:..|...|.
plant   261 DDKPDYSYLKRLFRDLFIREGYQFDYVFDWTVLKY-----PQI--GSSSGSSSRTRHHTTAKPGF 318

  Fly   323 -AAAVAAAAAASSHQQQQHKVNAAL------------GGGGGSAAQQQLQGGQTLAMLGGNGGGN 374
             |..:.........:..::|:..|:            .....|.::....|..:....|.:...|
plant   319 NADPIERQERILGKETTRYKIPGAVEAFSRRHPTTTSSPRDRSRSRNSDDGPFSKQTHGDSERAN 383

  Fly   375 GSQLIGGNGLNMDDSMAATNSSRPPY--DTPERRPSIRMRQGGGGGGGGVGVGGMPS 429
            .|.....:.   .....|.:||||..  ...|.|.|.|:....||||.|.| .|.||
plant   384 SSSRYRASS---SRKAVAASSSRPSSAGGPSESRTSSRLVSSSGGGGSGSG-NGRPS 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	192/273 (70%)
ckl7	NP_001330873.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	192/273 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	352	1.000	Domainoid score	I215
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	462	1.000	Inparanoid score	I362
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	1	1.000	-	-		otm2420
orthoMCL	1	0.900	-	-		OOG6_100396
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X224
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840