DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dco and ckl3

DIOPT Version :9

Sequence 1:	NP_001263132.1	Gene:	dco / 43673	FlyBaseID:	FBgn0002413	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001329054.1	Gene:	ckl3 / 829009	AraportID:	AT4G28880	Length:	415	Species:	Arabidopsis thaliana

Alignment Length:	426	Identity:	216/426 - (50%)
Similarity:	287/426 - (67%)	Gaps:	24/426 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGI 65
            ||..:|.||:||||||.||||:|:|.|.::|.|.||:|:|..:||||||..|:|.|:.::||.||
plant     1 MERIIGGKYKLGRKIGGGSFGEIFLATHVDTFEIVAVKIENSKTKHPQLLYEAKLYRILEGGSGI 65

  Fly    66 PRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIK 130
            |||.|.|.:|..|.:||:||||||||||.:|.|:||.||||:|||||::||:::||:.::|||||
plant    66 PRIKWFGVDGTENALVMDLLGPSLEDLFVYCGRKFSPKTVLMLADQMLTRIEFVHSKGYLHRDIK 130

  Fly   131 PDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195
            |||||||||:|.|.||:|||||||::|||.:.:||||||||||||||||||.|||||||||||||
plant   131 PDNFLMGLGRKANQVYLIDFGLAKRYRDANTNRHIPYRENKNLTGTARYASCNTHLGIEQSRRDD 195

  Fly   196 LESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHF 260
            ||||||||:||..|:||||||||.:|:|||::|.|||:||.|.||||..|.||.:|.::|..:.|
plant   196 LESLGYVLLYFLRGSLPWQGLKAVDKKQKYDKICEKKISTPIEVLCKNHPVEFASYFHYCHTLTF 260

  Fly   261 DQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQDGADGQAGHDAVAAAAA 325
            ||||||..|::|||:||.|.|:.:||:|||.::|:         ||||...:..   .||..::.
plant   261 DQRPDYGFLKRLFRDLFSREGYEFDYIFDWTIIKY---------QQAQKSRNQS---QAVPGSSN 313

  Fly   326 VAAAAAASSHQQQQHKVNAALGGGGGSAAQQQLQGGQTLAMLGGNGGGNGSQLIG---GNGLNMD 387
            ..|....:|:.:         ||...|...:..:..::...:|.:...|.:...|   |....:.
plant   314 PRAMPVDTSNHR---------GGPNISYEAEASERVRSANAIGPSPQINNNTAAGRTPGFDHPVH 369

  Fly   388 DSMAATNSSRPPYDTPERRPSIRMRQGGGGGGGGVG 423
            .:|...::|..|..|.:|.........|.|.|...|
plant   370 KNMNMPSTSLSPAGTSKRNVGPETSNSGYGSGNRTG 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	182/273 (67%)
ckl3	NP_001329054.1	PKc_like	8..282	CDD:419665	182/273 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	462	1.000	Inparanoid score	I362
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	1	1.000	-	-		otm2420
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X224
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980