DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dco and ckl5

DIOPT Version :9

Sequence 1:	NP_001263132.1	Gene:	dco / 43673	FlyBaseID:	FBgn0002413	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_179537.1	Gene:	ckl5 / 816466	AraportID:	AT2G19470	Length:	433	Species:	Arabidopsis thaliana

Alignment Length:	442	Identity:	233/442 - (52%)
Similarity:	300/442 - (67%)	Gaps:	38/442 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGI 65
            ||.|||||:||||||||||||:|||||.:.|.||||||||.::|.||||..||:.|:.:|||.||
plant     1 MEPRVGNKFRLGRKIGSGSFGEIYLGTDVQTNEEVAIKLESVKTAHPQLSYESRIYRVLQGGTGI 65

  Fly    66 PRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIK 130
            |.:.|.|.||||||:||:||||||||||::|.|:|||||||:||||||:|:::|||:.::|||||
plant    66 PNMKWYGVEGDYNVLVMDLLGPSLEDLFSYCKRQFSLKTVLMLADQMINRLEFIHSKSYLHRDIK 130

  Fly   131 PDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195
            |||||||||::.|.|||||:|||||:||:.:.:||||||||:|.||.||||:|||||||||||||
plant   131 PDNFLMGLGRRANQVYIIDYGLAKKYRDSSTHRHIPYRENKSLIGTPRYASLNTHLGIEQSRRDD 195

  Fly   196 LESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHF 260
            :|||||:||||..|:||||||||.||:|||::|||||:||||..||:|.|:||.:|.::||.:.|
plant   196 IESLGYILMYFLKGSLPWQGLKAGNKKQKYDKISEKKVSTSIETLCRGHPTEFASYFHYCRSLRF 260

  Fly   261 DQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQDGADGQAGHDAVAAAAA 325
            |.:|||.:|::||||||.|.||.:|:||||.:.|:         ||:|.|......||.....::
plant   261 DDKPDYAYLKRLFRNLFIREGFQFDFVFDWTVYKY---------QQSQSGNPQPRPHDGGVGTSS 316

  Fly   326 VAAAAAASSHQQQQHKVNAALGGGGGSAAQQQLQGGQTLAMLGGNGGGNG---SQLIGGNGLNMD 387
            ....|..:|.::.             ....|:.....||.....||..:.   .:|:.|: ||:.
plant   317 GLNPAVGNSEKRP-------------DVPNQRTNPDFTLKQKDKNGNDSAIAKDKLLPGS-LNLG 367

  Fly   388 DSMAATNSSRPPYDTPERRPSIRMRQGGGGGGGGV-----GVGGMPSGGGGG 434
            .|..  :|||...||..|.|.     .||......     |:.|:......|
plant   368 RSEG--SSSRRVVDTSSREPF-----SGGSDNANYETALKGIDGLRINNNAG 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	189/273 (69%)
ckl5	NP_179537.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	189/273 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	352	1.000	Domainoid score	I215
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	462	1.000	Inparanoid score	I362
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	1	1.000	-	-		otm2420
orthoMCL	1	0.900	-	-		OOG6_100396
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X224
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.880