Protein Alignment dco and VRK1

DIOPT Version :9

• Sequence 1: NP_001263132.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: XP_006720310.1
• Gene: VRK1 / 7443
• HGNCID: 12718
• Length: 420
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 99/322 - (30%)
• Similarity: 157/322 - (48%)
• Gaps: 41/322 - (12%)

  Fly     8 KYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQ----LHIESKFY------KTMQGG 62
            ::::|..||.|.||.||| ..:|:.|.|.....|:....|.    |..|.|||      :.:|..
Human    36 EWKVGLPIGQGGFGCIYL-ADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKW 99

  Fly    63 I--------GIPRIIWCGSEGD-----YNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMIS 114
            |        |:|: .|.....|     |..|:|:..|..|:.::...::|||.||||.|:.:::.
Human   100 IRTRKLKYLGVPK-YWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILD 163

  Fly   115 RIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNL--TGTA 177
            .::|||..:::|.|||..|.|:.. |..:.||::|:|||  :|......|..|:|:...  .||.
Human   164 ILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLA--YRYCPEGVHKEYKEDPKRCHDGTI 225

  Fly   178 RYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAAN-KRQKYERISEKKLSTSIVVL- 240
            .:.||:.|.|:..|||.|||.|||.::.:..|.|||:.    | |..||.|.|:.:...:|..|
Human   226 EFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWED----NLKDPKYVRDSKIRYRENIASLM 286

  Fly   241 --C---KGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGG 297
              |   |..|.|...|:...:.:.:.::|.|.:||.:.......:|...|...|.::::.||
Human   287 DKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGG 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	94/305 (31%)
VRK1	XP_006720310.1	STKc_VRK1	26..326	CDD:271024	94/298 (32%)
		S_TKc	37..293	CDD:214567	86/264 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810