DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dco and vrk3

DIOPT Version :9

Sequence 1:	NP_001263132.1	Gene:	dco / 43673	FlyBaseID:	FBgn0002413	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001013586.1	Gene:	vrk3 / 541443	ZFINID:	ZDB-GENE-030131-246	Length:	459	Species:	Danio rerio

Alignment Length:	226	Identity:	61/226 - (26%)
Similarity:	105/226 - (46%)	Gaps:	12/226 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 IGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHR 127
            :|||..:..|....|..:|...:|..|:...:..:...|.|.||.||.:::..:::||.:::.|.
Zfish   235 LGIPSCVGFGLHETYRFLVFPCMGQPLQTELDEGTGSLSEKNVLQLALRLLDSLEFIHEKEYAHA 299

  Fly   128 DIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLT--GTARYASINTHLGIEQ 190
            ||...|..: .......|::..||.|  ||.....||:.||:.....  |...:.|:::|.|...
Zfish   300 DIHAGNIYI-KSSSHTEVFLSGFGHA--FRFCPGGKHVEYRQGSRTAHQGNISFISLDSHKGAGP 361

  Fly   191 SRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLS--TSIVVLC---KGFPSEFVN 250
            |||.||:||||.::.:..|:|||..|...:.....|:  |:.:|  ..::..|   |...|....
Zfish   362 SRRSDLQSLGYCMLCWMTGSLPWSHLSHNSSSVAAEK--ERYMSDVPGLLTYCYKQKKASSALQE 424

  Fly   251 YLNFCRQMHFDQRPDYCHLRKLFRNLFHRLG 281
            ||.....:.:.::|||..|:...:....::|
Zfish   425 YLCNVMALQYTEKPDYTLLKGGLQQSLQKMG 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	61/226 (27%)
vrk3	NP_001013586.1	DUF4758	<9..>104	CDD:292572
		PK_VRK3	154..451	CDD:271026	60/220 (27%)
		SPS1	236..>384	CDD:223589	45/150 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810