DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dco and csnk1g1

DIOPT Version :9

Sequence 1:	NP_001263132.1	Gene:	dco / 43673	FlyBaseID:	FBgn0002413	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_009301749.1	Gene:	csnk1g1 / 494092	ZFINID:	ZDB-GENE-041212-63	Length:	466	Species:	Danio rerio

Alignment Length:	406	Identity:	186/406 - (45%)
Similarity:	266/406 - (65%)	Gaps:	26/406 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPR 67
            |.||..:|:|:|||.|:||::.||..:.|.|.||||||.::::.||||:|.:||||:....|:|:
Zfish    38 LMVGPNFRVGKKIGCGNFGELKLGKNLYTNEYVAIKLEPVKSRAPQLHLEYRFYKTLGSADGLPQ 102

  Fly    68 IIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPD 132
            :.:.|..|.||.||:|||||||||||:.|.|.|||||||::|.|:|||::|:||::.|:||:||:
Zfish   103 VFYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPE 167

  Fly   133 NFLMGL--GKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195
            |||:|.  .||.::::||||||||::.|..:.|||||||:|:|||||||.|||||||.|||||||
Zfish   168 NFLIGRQGNKKEHIIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDD 232

  Fly   196 LESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHF 260
            ||:||::.|||..|:||||||||...:::|::|.:.|.:|.|.|||:.||.|...||.:.|::.|
Zfish   233 LEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEVLCENFPEEMATYLRYVRRLDF 297

  Fly   261 DQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQDGADGQAGHDAVAAAAA 325
            .::|||.:||.||..||.|.|:.:||.:||     .|.:.|..:        |....|  :.|:|
Zfish   298 FEKPDYDYLRNLFTELFDRKGYAFDYSYDW-----VGRQIPTPV--------GTVHVD--SGASA 347

  Fly   326 VAAAAAASSHQQQQH---KVNAALGGGGGS---AAQQQLQGGQTLAMLGGNGGGNGSQLIGG-NG 383
            :...:.|...:..||   :...|:....|:   ...:|.......:.|..:..|...|::.. ||
Zfish   348 ITRESHAHRDRPSQHQPLRNQTAISDRRGAWEVQPNRQTNSSYLTSHLAADRHGGSVQVVSSTNG 412

  Fly   384 -LNMDDSMAATNSSRP 398
             ||.||.:|| :|:.|
Zfish   413 ELNADDPLAA-HSNAP 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	153/275 (56%)
csnk1g1	XP_009301749.1	STKc_CK1_gamma	43..330	CDD:271028	158/291 (54%)
		SPS1	43..>265	CDD:223589	129/221 (58%)
		CK1gamma_C	330..417	CDD:289378	18/96 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910