Protein Alignment dco and vrk2

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_957464.2
• Gene: vrk2 / 394145
• ZFINID: ZDB-GENE-040426-1046
• Length: 574
• Species: Danio rerio
• Alignment Length: 289
• Identity: 93/289 - (32%)
• Similarity: 144/289 - (49%)
• Gaps: 32/289 - (11%)

  Fly     9 YRLGRKIGSGSFGDIYLGT-----TINTGEEVAIKLECIRTKHPQLHIESKFY------KTMQ-- 60
            :|:|:.||.|.||.|||.:     .:....:..||:|  ..::..|..|.|||      :||.
Zfish    26 WRIGKMIGKGGFGLIYLASQDVNVPVRDDADFVIKVE--YHENGPLFSELKFYQRAAKPETMSKW 88

  Fly    61 ------GGIGIPRIIWCG---SEGD-YNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISR 115
                  |.:|||.....|   |.|. |..|||:.||..|:.:......:....:||.|...|:..
Zfish    89 MKSKQLGFLGIPTYWGSGLTESNGTRYRFMVMDRLGTDLQKVLIDNGGQLRKTSVLQLGVLMLDV 153

  Fly   116 IDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYREN--KNLTGTAR 178
            ::|||..:::|.|||..|.|:|. :..|.||:.|:||:  :|...:.:|..|:||  |...||..
Zfish   154 LEYIHDNEYVHADIKAANLLLGY-RDPNKVYLADYGLS--YRYCPNGEHKEYKENPKKGHNGTIE 215

  Fly   179 YASINTHLGIEQSRRDDLESLGYVLMYFNLGALPW-QGLKAANKRQKYERISEKKLSTSIVVLCK 242
            |.||:.|.|:..|||.||:.|||.|:::..|.||| ..||...:.|:.:......|..|::.:..
Zfish   216 YTSIDAHKGVAASRRGDLKVLGYCLLHWQCGTLPWLPSLKNPAEVQEAKAKLMSNLPDSVLKMST 280

  Fly   243 GFPS-EFVNYLNFCRQMHFDQRPDYCHLR 270
            ...| |...:|:..:.:.::::|||..||
Zfish   281 SSSSMEIAQFLSRVKDLGYNEKPDYQALR 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	93/289 (32%)
vrk2	NP_957464.2	STKc_VRK2	13..313	CDD:271025	93/289 (32%)