DRSC/TRiP Functional Genomics Resources

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Protein Alignment dco and Vrk1

DIOPT Version :9

Sequence 1:NP_001263132.1 Gene:dco / 43673 FlyBaseID:FBgn0002413 Length:440 Species:Drosophila melanogaster
Sequence 2:NP_001351296.1 Gene:Vrk1 / 22367 MGIID:1261847 Length:440 Species:Mus musculus


Alignment Length:391 Identity:110/391 - (28%)
Similarity:180/391 - (46%) Gaps:67/391 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 KYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQ----LHIESKFY------KTMQGG 62
            :::||..||.|.||.|||..| |:.:.|.....|:....|.    |..|.|||      :.:|..
Mouse    36 EWKLGLPIGQGGFGCIYLADT-NSSKPVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKW 99

  Fly    63 I--------GIPRIIWCGSEGD-----YNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMIS 114
            |        |:|: .|.....|     |..|:|:..|..|:.::...::|||.||||.|:.:::.
Mouse   100 IRTHKLKYLGVPK-YWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILD 163

  Fly   115 RIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNL--TGTA 177
            .::|||..:::|.|||..|.|:. .|..:.||::|:|||  :|......|..|:|:...  .||.
Mouse   164 ILEYIHEHEYVHGDIKASNLLLS-HKNPDQVYLVDYGLA--YRYCPDGVHKEYKEDPKRCHDGTL 225

  Fly   178 RYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQ-GLKAANKRQKYERISEKKLSTSIVVL- 240
            .:.||:.|.|:..|||.|||.|||.::.:..|.|||: .||..|    |.|.|:.:...::..| 
Mouse   226 EFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDNLKDPN----YVRDSKIRYRDNVAALM 286

  Fly   241 --C---KGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGG--- 297
              |   |..|.|...|:...:.:.:.::|.|.:||.:.......:|...|...|::.::.|.   
Mouse   287 EKCFPEKNKPGEIAKYMESVKLLEYTEKPLYQNLRDILLQGLKAIGSKDDGKLDFSAVENGSVKT 351

  Fly   298 -PRNPQAIQQAQDGA-----DGQAGHDAVAAAA-----------------AVAAAAAASSHQQQQ 339
             |.:.:..::|::.|     |.:.....|..||                 ..|..:::.|.::||
Mouse   352 RPASKKRKKEAEESAVCAVEDMECSDTQVQEAAQTRSVESQGAIHGSMSQPAAGCSSSDSSRRQQ 416

  Fly   340 H 340
            |
Mouse   417 H 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dcoNP_001263132.1 STKc_CK1_delta_epsilon 8..282 CDD:271027 94/305 (31%)
Vrk1NP_001351296.1 STKc_VRK1 26..326 CDD:271024 94/298 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 379..440 8/39 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1164
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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